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N,N'-DICYCLOHEXYLUREA

N,N'-DICYCLOHEXYLUREA structure

CAS No.: 2387-23-7

Chemical Name:: N,N'-DICYCLOHEXYLUREA

Synonyms: 1,3-DICYCLOHEXYLUREA;Indapamide Impurity 1;Dicyclohexylcarbodiamide;NSC 30023;NSC 17013;AURORA KA-3582;Lomustine USP RC C;N,N'-DICYCLOHEXYLUREA;n,n’-dicyclohexyl-ure;N,N'-DICYCLOHEXYLUREA

CBNumber:: CB2314754

Molecular Formula:: C13H24N2O

Molecular Weight:: 224.34

MDL Number:: MFCD00003829

MOL File:: 2387-23-7.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:12

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N,N'-DICYCLOHEXYLUREA Properties

Melting point	232-233 °C(lit.)
Boiling point	408℃
Density	1.02
refractive index	1.4832 (estimate)
Flash point	158℃
storage temp.	2-8°C
solubility	DMSO (Slightly, Heated), Methanol (Slightly)
form	Liquid
pka	13.89±0.20(Predicted)
color	Clear
Stability	Hygroscopic
InChIKey	ADFXKUOMJKEIND-UHFFFAOYSA-N
CAS DataBase Reference	2387-23-7(CAS DataBase Reference)
FDA UNII	ZV7823VVIM
EPA Substance Registry System	N,N'-Dicyclohexylurea (2387-23-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

Hazard Codes

Xn,N

Risk Statements

22-51/53

Safety Statements

WGK Germany

TSCA

Yes

HS Code

29242100

NFPA 704

	1
0		0

N,N'-DICYCLOHEXYLUREA price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHR2924	Lomustine Related Compound C certified reference material, pharmaceutical secondary standard	2387-23-7	500MG	$575	2024-03-01	Buy
Sigma-Aldrich	D80800	N,N′-Dicyclohexylurea 98%	2387-23-7	25g	$140	2024-03-01	Buy
Sigma-Aldrich	1369442	Lomustine Related Compound C United States Pharmacopeia (USP) Reference Standard	2387-23-7	25mg	$1500	2024-03-01	Buy
TCI Chemical	D0441	1,3-Dicyclohexylurea >98.0%(GC)(T)	2387-23-7	25g	$37	2024-03-01	Buy
TCI Chemical	D0441	1,3-Dicyclohexylurea >98.0%(GC)(T)	2387-23-7	500g	$274	2024-03-01	Buy

Product number	Packaging	Price	Buy
PHR2924	500MG	$575	Buy
D80800	25g	$140	Buy
1369442	25mg	$1500	Buy
D0441	25g	$37	Buy
D0441	500g	$274	Buy

N,N'-DICYCLOHEXYLUREA Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

N,N''-Dicyclohexylurea,is a substituted Urea (U822500) compound, which has shown to be a potent inhibitor of juvenile hormone epoxide hydrolase (JHEH) of the tobacco hornworm M. sexta. Lomustine USP Related Compound C.

Preparation

An excess of dry ice (200 g) was added gradually to a solution of dicyclohexylcarbodiimide (2.06 g, 0.01 mol), cyclohexylamine (1.98 g, 0.02 mol), and triethylamine (2.2 g, 0.02 mol) in THF at 75 ℃ over a period of 8 h. After stirring for 8 h, the reaction mixture was concentrated under reduced pressure and the resultant precipitate was collected. Fractional recrystallization of the precipitate from acetone/methanol gave N,N'-dicyclohexylurea; yield 2.2 g (98% based on dicyclohexylcarbodiimide and cyclohexylamine).

Definition

ChEBI: 1,3-dicyclohexylurea is a member of ureas.

Synthesis Reference(s)

The Journal of Organic Chemistry, 61, p. 4175, 1996 DOI: 10.1021/jo9522825

N,N'-DICYCLOHEXYLUREA synthesis

Synthesis of N,N'-DICYCLOHEXYLUREA from Cyclohexylamine and Urea

N,N'-DICYCLOHEXYLUREA Preparation Products And Raw materials

Raw materials

Cyclohexylamine 3-Methyl-1-butanol TRILINOLENIN gamma-Linolenic acid Isocyanatocyclohexane

Preparation Products

Dicyclohexylcarbodiimide N,N'-DICYCLOHEXYLOXAMIDE 1-cyclohexylaminopropan-2-ol Bisphenol A 5-DIAZOMELDRUM'S ACID

Ethyl N-cyclohexylurethane L-Alanyl-L-proline N-Methylcyclohexylamine

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N,N'-DICYCLOHEXYLUREA Suppliers

Global( 227)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9641	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Xi'an Kono chem co., Ltd.,	58
Hubei xin bonus chemical co. LTD	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Antai Fine Chemical Technology Co.,Limited	58
TargetMol Chemicals Inc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from N,N'-DICYCLOHEXYLUREA manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-14	N,N'-DICYCLOHEXYLUREA 2387-23-7	US $1.00 / KG	1KG	99%	25kg	Career Henan Chemical Co
	2019-07-06	N,N'-DICYCLOHEXYLUREA 2387-23-7	US $8.80 / KG	1KG	97%-99%	100kg	Career Henan Chemical Co

N,N'-DICYCLOHEXYLUREA
2387-23-7
US $1.00 / KG
99%
Career Henan Chemical Co

N,N'-DICYCLOHEXYLUREA
2387-23-7
US $8.80 / KG
97%-99%
Career Henan Chemical Co

N,N'-DICYCLOHEXYLUREA Spectrum

N,N'-DICYCLOHEXYLUREA(2387-23-7)MS N,N'-DICYCLOHEXYLUREA(2387-23-7)¹HNMR N,N'-DICYCLOHEXYLUREA(2387-23-7)¹³CNMR N,N'-DICYCLOHEXYLUREA(2387-23-7)IR1 N,N'-DICYCLOHEXYLUREA(2387-23-7)IR2 N,N'-DICYCLOHEXYLUREA(2387-23-7)Raman

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AURORA KA-3582 n,n’-dicyclohexyl-ure N,N'-DICYCLOHEXYLUREA N,N,-Dicyclohexylurea98.% N,N'-Carbonylbis(cyclohexanamine) NSC 17013 NSC 30023 LoMustine Related CoMpound C 1,3-Dicyclohexylurea for synthesis Lomustine EP Impurity B 5-cyanobenzene-1,3-dicarboxylic acid 1,3-Dicyclohexylurea > Lomustine USP RC C Urea, N,N'-dicyclohexyl- Lomustine Related Compound C (1,3-Dicyclohexylurea) (1369442) 1,3-DICYCLOHEXYLUREA Dicyclohexylcarbodiamide Indapamide Impurity 1 Lomustine USP Related Compound C Lomustine EP Impurity C Lomustine Impurity 3(Lomustine EP Impurity C)(Lomustine USP RC C) 1,3-dicyclohexylurea - impurity 1,3-Dicyclohexylurea, ≥ 98.0% n,n''-dicyclohexylurea N,N'-DICYCLOHEXYLUREA 2387-23-7 C13H24N2O C6H11NHCONHC6H11 Organic Building Blocks Ureas Building Blocks Carbonyl Compounds Finasteride Carbonyl Compounds Organic Building Blocks Ureas