3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE
- CAS No.
- 9040-59-9
- Chemical Name:
- 3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE
- Synonyms
- PDE 3B;EC 3.1.4.17;Phosphodiesterase 3B;(4-Nitrobenzyl)arsonic acid;Phosphodiesterasefrombovinebrain;Phosphodiesterase 3B, Recombinant;3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE;PHOSPHODIESTERASE 3':5'-CYCLIC NUCLEOTIDE;Phosphodiesterase, cyclic 3',5'-nucleotide;Phosphodiesterase 3A from Human, Recombinant
- CBNumber:
- CB2437361
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00131864
- MOL File:
- Mol file
storage temp. | -20°C |
---|---|
form | lyophilized powder |
EWG's Food Scores | 1 |
3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | P9529 | Phosphodiesterase, 3′,5′-cyclic-nucleotide-specific from bovine brain 15-30?units/mg protein (in the presence of 0.03 mM Ca2+ and a saturating level (10 units per ml) of calmodulin (P2277)), lyophilized powder | 9040-59-9 | 1unit | $471 | 2022-05-15 | Buy |
American Custom Chemicals Corporation | ENZ0000358 | 3',5'-CYCLIC-NUCLEOTIDE-5'-NUCLEOTIDOHYDROLASE 95.00% | 9040-59-9 | 5MG | $500.81 | 2021-12-16 | Buy |
3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE Chemical Properties,Uses,Production
Uses
Phosphodiesterase, 3′,5′-cyclic-nucleotide-specific from bovine brain has been used to assay the protein activator, calmodulin and in in vitro adenylate cyclase assay.
Uses
For use in calmodulin (P 0270) assay. Activity is reduced to <50% without calmodulin present.
General Description
Phosphodiesterase (PDE1) exists in two isoforms -PDE1A2 and PDE1B1. The enzyme has a role in the complex interaction between cyclic nucleotides and Ca2+ second-messenger systems.
Biochem/physiol Actions
Hydrolyzes the 3′,5′-phosphodiester bond in cyclic nucleotide monophosphates, such as cAMP and cGMP, to the corresponding nucleotide 5′-monophosphate.
Clinical Use
Phosphodiesterase-3 (PDE3) is an enzyme responsible for degradation of cAMP to AMP in platelets and blood vessels. Selective cAMP PDE3 inhibitors, such as dipyridamole and cilostazol , inhibit the degradation of cAMP, thereby increasing cellular concentration of cAMP and leading to inhibition of platelet aggregation and vasodilation.
3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE Preparation Products And Raw materials
Raw materials
Preparation Products
3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21688 | 55 |
Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
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Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
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Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
Shanghai Yingxin laboratory equipment Co., Ltd | 021-021-59178156 15300768757 | 359382369@qq.com | China | 10678 | 58 |
Shanghai Guchen Biotechnology Co., LTD | 021-34675735 19147740836 | 1986399151@qq.com | China | 9849 | 58 |
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