ChemicalBook >> CAS DataBase List >>O-Desmorpholinopropyl Gefitinib
O-Desmorpholinopropyl Gefitinib
- CAS No.
- 184475-71-6
- Chemical Name:
- O-Desmorpholinopropyl Gefitinib
- Synonyms
- 4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-ol;FAAH-IN-2;Des-Gefitinib;N-(3-Chloro-4-f;FAAH inhibitor 2;Gefitinib iMpurity C;Gefitinib Intermediate 1;Gefitinib interMediate VII;FAAH-IN-2 (Gefitinib Impurity);O-Desmorpholinopropyl Gefitinib
- CBNumber:
- CB31176644
- Molecular Formula:
- C15H11ClFN3O2
- Molecular Weight:
- 319.72
- MDL Number:
- MFCD09908046
- MOL File:
- 184475-71-6.mol
- MSDS File:
- SDS
Last updated:2024-03-27 11:08:09
| Melting point | >260°C (dec.) |
|---|---|
| Boiling point | 478.8±45.0 °C(Predicted) |
| Density | 1.489±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Methanol (Very Slightly, Heated) |
| form | Solid |
| pka | 8.18±0.40(Predicted) |
| color | Pale Beige to Beige |
| FDA UNII | V26QDI5C8D |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933.59.8000 |
O-Desmorpholinopropyl Gefitinib price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C3647 | 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol | 184475-71-6 | 1G | $64 | 2024-03-01 | Buy |
| TCI Chemical | C3647 | 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol | 184475-71-6 | 5G | $218 | 2024-03-01 | Buy |
| TRC | D296830 | O-DesmorpholinopropylGefitinib | 184475-71-6 | 5g | $225 | 2021-12-16 | Buy |
| Usbiological | 008737 | O-Desmorpholinopropyl Gefitinib | 184475-71-6 | 100mg | $418 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21367 | O-Desmorpholinopropyl gefitinib | 184475-71-6 | 5G | $550 | 2021-12-16 | Buy |
O-Desmorpholinopropyl Gefitinib Chemical Properties,Uses,Production
Description
O-Desmorpholinopropyl Gefitinib is a metabolite of Gefitinib, a potent inhibitor of tyrosine phosporylation in EGFR. The chemical structure of O-Desmorpholinopropyl Gefitinib consists of a quinazoline-6-ol core with a phenylamino group attached to a chloro-fluoro-phenyl ring, enabling it to interact with multiple biological targets. It is involved in inhibiting enzymes such as cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS).
Chemical Properties
Tan Solid
Uses
A metabolite of Gefitinib.
Definition
ChEBI: O-Desmorpholinopropyl Gefitinib is a member of quinazolines.
Synthesis of O-Desmorpholinopropyl Gefitinib from 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate
O-Desmorpholinopropyl Gefitinib Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 210)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Yangzhou Qinyuan Pharmatech Co.,ltd | +86-18752526868 | jennysun@yzqyyykj.com | China | 64 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 18232 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15957 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 | chloewu@chicopharm.cn | CHINA | 341 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2966 | 58 |
View Lastest Price from O-Desmorpholinopropyl Gefitinib manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-09 | 4-(3-chloro-4-fluorophenylami-no)-7-methoxyquinazolin-6-ol
184475-71-6
|
US $0.00-0.00 / kg | 1kg | 99%(HPLC) | 5000kg | Nanjing Fred Technology Co., Ltd | |
 |
2024-03-27 | 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
184475-71-6
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2022-06-22 | 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
184475-71-6
|
US $0.00 / g | 10g | 98% | 10tons | Yangzhou Qinyuan Pharmatech Co.,ltd |
-
- 4-(3-chloro-4-fluorophenylami-no)-7-methoxyquinazolin-6-ol
184475-71-6
- US $0.00-0.00 / kg
- 99%(HPLC)
- Nanjing Fred Technology Co., Ltd
-
- 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
184475-71-6
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
184475-71-6
- US $0.00 / g
- 98%
- Yangzhou Qinyuan Pharmatech Co.,ltd
184475-71-6(O-Desmorpholinopropyl Gefitinib)Related Search:
Gefitinib Impurity 11
Gefitinib-d6
6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
1of4
FAAH-IN-2
4-(3-Chloro-4-fluorophenylamino)-6-hydroxy-7-methoxyquinazoline
4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol
O-Desmorpholinopropyl Gefitinib
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Gefitinib interMediate VII
4-(3-Chlor-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Gefitinib Intermediate 1
4-(3-Chloro-4-fluoroanilino)-6-hydroxy-7-methoxyquinazoline
N-(3-Chloro-4-f
6-Quinazolinol,4-[(3-chloro-4-fluorophenyl)aMino]-7-Methoxy-
Gefitinib iMpurity C
FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib)
Gefitinib Impurity 12 (O-Desmorpholinopropyl Gefitinib)
FAAH inhibitor 2
Gefitinib O-Desmorpholinopropyl Impurity
4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-ol
Des-Gefitinib
FAAH-IN-2 (Gefitinib Impurity)
4- (3-Chloro-4-fluorophenylamino) -7-methoxyquinoline-6-alcohol
184475-71-6
C15H11ClFN3O2
Gefitinib
Various Metabolites and Impurities
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals