HYDROXYDIONESODIUM
- CAS No.
- 53-10-1
- Chemical Name:
- HYDROXYDIONESODIUM
- Synonyms
- Viadril;Presuren;HYDROXYDION;HYDROXYDIONESODIUM;Hydroxidioni natrii succinas;Hidroxidiona succinato sodico;HYDROXYDIONESODIUMSUCCINATE USP/EP/BP;Hidroxidiona succinato sodico [inn-spanish];21-Hydroxypregnane-3,20-dione sodium hemisuccinate;Succinic acid 1-sodium 4-(3,20-dioxo-5β-pregnane-21-yl)
- CBNumber:
- CB31406549
- Molecular Formula:
- C25H35NaO6
- Molecular Weight:
- 454.54
- MDL Number:
- MFCD00864451
- MOL File:
- 53-10-1.mol
- MSDS File:
- SDS
| EWG's Food Scores | 1 |
|---|---|
| FDA UNII | 53J8I8O5EW |
HYDROXYDIONESODIUM price
HYDROXYDIONESODIUM Chemical Properties,Uses,Production
Originator
Viadril,Pfizer,US,1957
Manufacturing Process
A solution of 20 g of desoxycorticosterone in 190 ml of absolute ethanol was
stirred in an atmosphere of hydrogen in the presence of 1.68 g of 25%
palladium on calcium carbonate catalyst. After 20 hours, approximately 1
molar equivalent of hydrogen had been absorbed and hydrogen uptake had
ceased. The catalyst was removed by filtration and the filtrate evaporated in
vacuo to yield 20 g of nearly pure product, MP 135°C to 140°C. The crude
product was demonstrated to be free of starting material by paper
chromatography. A highly purified product was obtained by recrystallization
from acetone-water with cooling in an ice bath, yield 14.5 g, MP 152°C to
154°C. The product was characterized by analysis and by absence of
ultraviolet absorption.
A solution of 14 g of 21-hydroxypregnane-3,20-dione and of 14 g of
recrystallized succinic anhydride in 140 ml of dry pyridine was allowed to
stand at room temperature for 18 hours, then cooled in an ice bath and
poured in a fine stream into 1.5 liters of ice water. Excess pyridine was
neutralized with 3N hydrochloric acid and the solution further diluted with 2
liters of ice water. The precipitated product was filtered, washed with water
and dried in vacuo at 50°C affording 18 g of solid MP 192°C to 195°C.
Recrystallization of a small sample afforded analytically pure material, MP
200°C.
Therapeutic Function
Anesthetic
HYDROXYDIONESODIUM Preparation Products And Raw materials
HYDROXYDIONESODIUM Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 27945 | 58 |
| Supplier | Advantage |
|---|---|
| Dideu Industries Group Limited | 58 |
View Lastest Price from HYDROXYDIONESODIUM manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-09 | HYDROXYDIONESODIUMSUCCINATE USP/EP/BP | US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
-
- HYDROXYDIONESODIUMSUCCINATE USP/EP/BP
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited