N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide
![N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide Structure](CAS/GIF/67605-85-0.gif)
- CAS No.
- 67605-85-0
- Chemical Name:
- N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide
- Synonyms
- C4AHL;C4-HSL;Ch-homoserinelactone;N-butyryl-L-Homoserine;Butyryl-L-hoMoserine lactone;N-butyryl-L-Homoserine lactone;N-[(3S)-2-oxooxolan-3-yl]butanamide;N-(2-oxotetrahydrofuran-3-yl)butanamide;(S)-N-(2-Oxotetrahydrofuran-3-yl)butyraMide;C4-HSL, N-Butyryl-L-hoMoserine lactone, PAI
- CBNumber:
- CB32489923
- Molecular Formula:
- C8H13NO3
- Molecular Weight:
- 171.19
- MDL Number:
- MFCD12912262
- MOL File:
- 67605-85-0.mol
- MSDS File:
- SDS
| Melting point | 120-123 °C |
|---|---|
| Boiling point | 428.1±34.0 °C(Predicted) |
| Density | 1.13 |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Solid |
| pka | 14.78±0.20(Predicted) |
| color | White to Off-White |
| Stability | Stable under recommended storage conditions., Stable Under Recommended Storage C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| NFPA 704 |
|
N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML3427 | C4-HSL ≥95% (HPLC) | 67605-85-0 | 10MG | $79 | 2023-06-20 | Buy |
| Sigma-Aldrich | SML3427 | C4-HSL ≥95% (HPLC) | 67605-85-0 | 50MG | $255 | 2023-06-20 | Buy |
| Cayman Chemical | 10007898 | N-butyryl-L-Homoserine lactone ≥95% | 67605-85-0 | 5mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 10007898 | N-butyryl-L-Homoserine lactone ≥95% | 67605-85-0 | 10mg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 10007898 | N-butyryl-L-Homoserine lactone ≥95% | 67605-85-0 | 25mg | $116 | 2024-03-01 | Buy |
N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide Chemical Properties,Uses,Production
Description
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-butyryl-L-Homoserine lactone is a quorum-sensing signaling molecule produced by P. aeruginosa. It induces expression of the virulence genes lasB and rhlA in P. aeruginosa when used at a concentration of 10 μM. N-butyryl-L-Homoserine lactone (50 μM) induces rhamnolipid accumulation in P. aeruginosa growth media.
Uses
N-butyryl-L-Homoserine lactone is a diffusable quorum sensing lactone.
Uses
Butyryl-L-homoserine lactone is a short acylhomoserine lactone isolated from Pseudomonas aeruginosa in 1995 and demonstrated to be a quorum sensing modulator in biofilms. Acylhomoserine lactones have been detected in hundreds of bacterial species and, while the homologues vary between species and strains, the homoserine lactones are the major chemical modulators of within and between cell communication and regulation. The most significant variable defining the function of the homoserine lactone is the length of the acyl chain, with shorterchains displaying opposing actions to the longer chains.
Definition
ChEBI: (+)-a(S)-butyr-amido-r-butyrolactone is a N-acyl-amino acid.
N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| GL Biochem (Shanghai) Ltd. | +86-021-61263370 +86-18901917034 | CHINA | 3904 | 58 | |
| GL Biochem(Binhai) Ltd. | +86-021-61263370 +8615301650015 | wuqiuyan@glschina.com | China | 2975 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52861 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | alfa4@alfachem.cn | China | 13039 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |