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2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID

2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID structure

CAS No.: 4746-63-8

Chemical Name:: 2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID

Synonyms: Aclidinium Impurity 3;Dithienylglycolic acid;Di-2-thienylglycolic Acid;Titropium bromide EP impurity A;Tiotropium Bromide EP Impurity A;2-HYDROXY-2,2-DITHIOPHEN-2-YLACETICACID;2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID;2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-;Tiotropium Bromide EP Impurity B (Aclidinium Impurity 3);Tiotropium Bromide Impurity 1(Tiotropium Bromide EP Impurity A)

CBNumber:: CB3749100

Molecular Formula:: C10H8O3S2

Molecular Weight:: 240.29

MDL Number:: MFCD04038827

MOL File:: 4746-63-8.mol

MSDS File:: SDS

Last updated:2023-04-23 13:52:06

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2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID Properties

Melting point	93 °C
Boiling point	436.5±40.0 °C(Predicted)
Density	1.527±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Sparingly), Methanol (Slightly, Sonicated)
form	Solid
pka	2.79±0.25(Predicted)
color	Light Grey to Black
Stability	Light Sensitive
FDA UNII	RI3X2J9148

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	D493915	Di-2-thienylglycolicAcid	4746-63-8	250mg	$185	2021-12-16	Buy
Biosynth Carbosynth	IH41893	2-Hydroxy-2,2-bis(2-thienyl) acetic acid	4746-63-8	5G	$300	2021-12-16	Buy
Medical Isotopes, Inc.	106176	2-Hydroxy-2-2-bis(2-thienyl)aceticacid	4746-63-8	25mg	$350	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0149604	2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID 95.00%	4746-63-8	5MG	$497.86	2021-12-16	Buy
Biosynth Carbosynth	IH41893	2-Hydroxy-2,2-bis(2-thienyl) acetic acid	4746-63-8	10g	$500	2021-12-16	Buy

Product number	Packaging	Price	Buy
D493915	250mg	$185	Buy
IH41893	5G	$300	Buy
106176	25mg	$350	Buy
CHM0149604	5MG	$497.86	Buy
IH41893	10g	$500	Buy

2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID Chemical Properties,Uses,Production

Uses

Di-2-thienylglycolic Acid is an analog of Methyl Di(2-thienylglycolate) (M303765), an intermediate in the production of Tiotropium Bromide (T444850), a long-acting bronchodilator.

2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Methyl 2,2-dithienylglycolate

2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID Suppliers

Global( 78)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10326	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	6854	65

Supplier	Advantage
Standardpharm Co. Ltd.	58
Hubei Ipure Biology Co., Ltd	58
sgtlifesciences pvt ltd	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
China National Standard Pharmaceutical Corporation Limited	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
J & K SCIENTIFIC LTD.	76
Chemsky（shanghai）International Co.,Ltd.	50
Daicel Chiral Technologies (China)CO.,LTD	65

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2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID Di-2-thienylglycolic Acid 2-HYDROXY-2,2-DITHIOPHEN-2-YLACETICACID Aclidinium Impurity 3 Tiotropium Bromide Impurity 1(Tiotropium Bromide EP Impurity A) Tiotropium Bromide EP Impurity A 2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl- Tiotropium Bromide EP Impurity B (Aclidinium Impurity 3) Dithienylglycolic acid Titropium bromide EP impurity A 4746-63-8 C10H8O3S2 Sulphur Derivatives Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals