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(R)-1-Boc-3-methylpiperazine

(R)-1-Boc-3-methylpiperazine Structure
(R)-1-Boc-3-methylpiperazine structure
CAS No.
163765-44-4
Chemical Name:
(R)-1-Boc-3-methylpiperazine
Synonyms
tert-butyl (R)-3-methylpiperazine-1-carboxylate;(R)-4-N-BOC-2-METHYLPIPERAZINE;(R)-tert-butyl 3-Methylpiperazine-1-carboxylate;(R)-4-Boc-2-Methylpi;(R)-N-BOC-2-METHYLPIPERAZINE;(R)-4-BOC-2-METHYLPIPERAZINE;(R)-1-BOC-3-METHYLPIPERAZINE;(R)-N4-BOC-2-METHYLPIPERAZINE;(3R)-1-BOC-3-METHYLPIPERAZINE;(R)-3-Methyl-1-Boc-piperazine
CBNumber:
CB4192376
Molecular Formula:
C10H20N2O2
Molecular Weight:
200.28
MDL Number:
MFCD02683205
MOL File:
163765-44-4.mol
MSDS File:
SDS
Last updated:2023-12-18 16:59:08
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(R)-1-Boc-3-methylpiperazine Properties

Melting point 40-45 °C
Boiling point 268.7±15.0 °C(Predicted)
Density 0.997±0.06 g/cm3(Predicted)
Flash point 223 °F
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 8.52±0.40(Predicted)
form Crystalline Powder
color White
optical activity [α]/D +16±2°, c = 1 in dioxane
InChIKey FMLPQHJYUZTHQS-MRVPVSSYSA-N
CAS DataBase Reference 163765-44-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  37/38-41-36/37/38
Safety Statements  26-39-37/39
WGK Germany  3
F  10-34
HS Code  29335990
NFPA 704
1
2 0

(R)-1-Boc-3-methylpiperazine price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar H27350 (R)-(+)-1-Boc-3-methylpiperazine, 97% 163765-44-4 1g $69.65 2024-03-01 Buy
Alfa Aesar H27350 (R)-(+)-1-Boc-3-methylpiperazine, 97% 163765-44-4 5g $212.65 2024-03-01 Buy
Sigma-Aldrich 674761 (R)-1-Boc-3-methylpiperazine 97% 163765-44-4 1g $90.7 2024-03-01 Buy
TRC B656835 (R)-4-Boc-2-methylpiperazine 163765-44-4 10g $160 2021-12-16 Buy
TRC B656835 (R)-4-Boc-2-methylpiperazine 163765-44-4 250g $1375 2021-12-16 Buy
Product number Packaging Price Buy
H27350 1g $69.65 Buy
H27350 5g $212.65 Buy
674761 1g $90.7 Buy
B656835 10g $160 Buy
B656835 250g $1375 Buy

(R)-1-Boc-3-methylpiperazine Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

(R)-4-Boc-2-methylpiperazine is a reagent used in organic synthesis. Used in the synthesis of orally bioavailable inhibitors of 11-β-hydroxysteroid. (R)-4-Boc-2-methylpiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

To a solution of (R)-methylpiperazine (400 mg) in dichloromethane (20 mL) at 0 ℃ was added di-tert-butyl dicarbonate (871 mg). The reaction was stirred at room temperature for 4 h and then quenched with water (20 mL), followed by extraction into dichloromethane (2 x 40 mL). The combined organics were washed with saturated aqueous brine solution (40 mL), dried (MgSO4), and concentrated to give (R)-1-Boc-3-methylpiperazine as a white solid (669 mg, 84%).

(R)-4-Boc-2-methylpiperazine

(R)-1-Boc-3-methylpiperazine synthesis

24424-99-5
75336-86-6
163765-44-4
Synthesis of (R)-1-Boc-3-methylpiperazine from Di-tert-butyl dicarbonate and (R)-(-)-2-Methylpiperazine

(R)-1-Boc-3-methylpiperazine Preparation Products And Raw materials

Raw materials

(R)-(-)-2-Methylpiperazine Di-tert-butyl dicarbonate 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile

Preparation Products

(R)-1,2-DIMETHYL-PIPERAZINE

(R)-1-Boc-3-methylpiperazine Suppliers

Global( 285)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Boc Chemical Co., Ltd.
021-34975602; +8618721111801 shangli@bocchem.com China 138 58
Shanghai UCHEM Inc. 		+862156762820 +86-13564624040 sales@myuchem.com China 6709 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Chembon Pharmaceutical Co., Ltd. 		+86-28-8425-2981 CHINA 724 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9341 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 7019 58
Accela ChemBio Inc. 		(+1)-858-699-3322 info@accelachem.com United States 19965 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Supplier Advantage
Shanghai Boc Chemical Co., Ltd.
58
Shanghai UCHEM Inc. 		58
Capot Chemical Co.,Ltd. 		60
Chembon Pharmaceutical Co., Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
Accela ChemBio Inc. 		58
Chongqing Chemdad Co., Ltd 		58

View Lastest Price from (R)-1-Boc-3-methylpiperazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-4-Boc-2-methylpiperazine pictures 2024-02-23 (R)-4-Boc-2-methylpiperazine
163765-44-4
 US $37.00-788.00 / g 10g 0.99 25kg Shanghai UCHEM Inc.
(R)-4-Boc-2-methylpiperazine pictures 2023-01-18 (R)-4-Boc-2-methylpiperazine
163765-44-4
 US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
(R)-4-N-Boc-2-methylpiperazine pictures 2022-02-10 (R)-4-N-Boc-2-methylpiperazine
163765-44-4
 US $0.00 / KG 1KG 99.3% 100 tons Honest Joy Holdings Limited

(R)-1-Boc-3-methylpiperazine Spectrum

(R)-4-Boc-2-methylpiperazine(163765-44-4)1HNMR(R)-4-Boc-2-methylpiperazine(163765-44-4)FT-IR

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1of4

(R)-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-N-BOC-2-METHYLPIPERAZINE (R)-N4-BOC-2-METHYLPIPERAZINE TERT-BUTYL (R)-3-METHYL-1-PIPERAZINECARBOXYLATE (R)-4-BOC-2-METHYLPIPERAZINE (R)-3-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-1-BOC-3-METHYLPIPERAZINE (R)-1-TERT-BUTOXYCARBONYL-3-METHYLPIPERAZINE (R)-1-N-BOC-3-METHYLPIPERAZINE (R)-3-Methyl-1-Boc-piperazine (3R)-1-BOC-3-METHYLPIPERAZINE 4-BOC-2-(R)-METHYL-PIPERAZINE 1-PIPERAZINECARBOXYLIC ACID, 3-METHYL-, 1,1-DIMETHYLETHYL ESTER, (3R)- (S)-1-BOC-3-METHYL-PIPERAZINE,(R)-1-Boc-3-methylpiperazine (R)-4-N-Boc-2-methylpiperazine (R )-4-N-Boc-2-methyl piperazine (R)-2-Methylpiperazine, N4-BOC protected (R)-1-Boc-3-methylpiperazine, tert-Butyl (R)-3-methyl-1-piperazinecarboxylate (R)-4-Boc-2-piperazinecarboxylic acid (R)-3-Methyl-Piperazine-1-Carbo (3R)-3-Methylpiperazine, N1-BOC protected tert-Butyl (R)-3-methyl-1-piperazinecarboxylate acid tert-Butyl (3R)-3-methylpiperazine-1-carboxylate (R)-4-N-BOC-2-METHYL-PIPERAZINE-HCl (R)-4-Boc-2-Methylpi (R)-(+)-1-Boc-3-Methylpiperazine (R)-4-N-Boc-2-Methyl-piperazine/(R)-1-Boc-3-Methylpiperazine (R)-butyl 3-Methylpiperazine-1-carboxylate (R)-(+)-1-Boc-3-methylpiperazine,97% tert-Butyl (3R)-3-methylpiperazine-1-carboxylate, (3R)-1-(tert-Butoxycarbonyl)-3-methylpiperazine (R)-4-N-BOC-2-METHYLPIPERAZINE (R)-tert-butyl 3-Methylpiperazine-1-carboxylate tert-butyl (R)-3-methylpiperazine-1-carboxylate 1-Piperazinecarboxylic acid, 3-methyl-, 1,1-dimethylethyl ester, (3R)- (9CI, ACI) 3-methyl-1-Piperazinecarboxylic acid 1,1-dimethylethyl ester (3R)- (9CI ACI) (R)-tert-butyl-2- methylpiperazine-4-carboxylate 163765-44-4 345-75-7 C10H20N2O2 Chiral Building Blocks Asymmetric Synthesis Heterocyclic Building Blocks Piperazines Piperaizine Piperazine series pharmacetical Piperazines