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GGTI-2133

GGTI-2133 Structure
GGTI-2133 structure
CAS No.
Chemical Name:
GGTI-2133
Synonyms
GGTI-2133;4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE
CBNumber:
CB4369293
Molecular Formula:
C27H26N4O3
Molecular Weight:
454.52
MDL Number:
MFCD02683592
MOL File:
Mol file
Last updated:2023-04-23 13:52:06
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GGTI-2133 Properties

Melting point 103-118.5 °C
storage temp. -20°C
form solid
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

GGTI-2133 Chemical Properties,Uses,Production

Uses

GGTI-2133 i an inhibitors of protein geranylgeranyltransferase-I. Increases prelamin A accumulation by inhibiting ZMPSTE24 protein in human fibroblast. GGTI-2133 inhibited proliferation and migration via involvement of RhoA and RalB proteins in human oral squamous cell carcinoma cell.

GGTI-2133 Preparation Products And Raw materials

Raw materials

Preparation Products

GGTI-2133 Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
VDM Biochemicals 0330-2528181 sales@vdmbio.com United States 510 64
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
VDM Biochemicals 64
Sigma-Aldrich 80
4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE GGTI-2133 C27H28N4O3C2HF3O2 A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I