Inositol nicotinate
- CAS No.
- 6556-11-2
- Chemical Name:
- Inositol nicotinate
- Synonyms
- INOSITOL;INOSITOL HEXANICOTINATE;hexanicotinate;dilcit;Palohex;WIN9154;hexopal;linodil;mesonex;mesotal
- CBNumber:
- CB4411387
- Molecular Formula:
- C42H30N6O12
- Molecular Weight:
- 810.72
- MDL Number:
- MFCD00006387
- MOL File:
- 6556-11-2.mol
- MSDS File:
- SDS
| Melting point | 254-256 °C(lit.) |
|---|---|
| Boiling point | 755.54°C (rough estimate) |
| Density | 1.3348 (rough estimate) |
| refractive index | 1.6400 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Aqueous Acid (Slightly, Heated), DMSO (Slightly, Heated, Sonicated) |
| form | Solid |
| pka | 3.92±0.10(Predicted) |
| color | White to Off-White |
| Merck | 13,5002 |
| InChIKey | MFZCIDXOLLEMOO-GYSGTQPESA-N |
| SMILES | [C@@H]1(OC(C2=CC=CN=C2)=O)[C@@H](OC(C2=CC=CN=C2)=O)[C@H](OC(C2=CC=CN=C2)=O)[C@@H](OC(C2=CC=CN=C2)=O)[C@H](OC(C2=CC=CN=C2)=O)[C@@H]1OC(C1=CC=CN=C1)=O |
| LogP | 3.945 (est) |
| CAS DataBase Reference | 6556-11-2(CAS DataBase Reference) |
| FDA UNII | A99MK953KZ |
| ATC code | C04AC03 |
| EPA Substance Registry System | Inositol nicotinate (6556-11-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H315 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 2 |
| RTECS | NM7535400 |
Inositol nicotinate price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | I666070 | myo-InositolHexanicotinate | 6556-11-2 | 25g | $145 | 2021-12-16 | Buy |
| Usbiological | 293814 | Inositol nicotinate | 6556-11-2 | 1g | $345 | 2021-12-16 | Buy |
| Biosynth Carbosynth | MI33322 | Inositol nicotinate | 6556-11-2 | 1kg | $400 | 2021-12-16 | Buy |
| Biosynth Carbosynth | MI33322 | Inositol nicotinate | 6556-11-2 | 2Kg | $600 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 70909 | myo-InositolHexanicotinate | 6556-11-2 | 250mg | $620 | 2021-12-16 | Buy |
Inositol nicotinate Chemical Properties,Uses,Production
Originator
Hexanicotol,Philadelphia,US,1962
Uses
benzidine substitute
Uses
myo-Inositol Hexanicotinate is an nicotinate conjugate of myo-inositol, an structural basis for a number of secondary messengers.
Definition
ChEBI: Inositol hexanicotinate is an inositol nicotinate. It is functionally related to a nicotinic acid.
Manufacturing Process
100 g of nicotinic acid were suspended in 265 ml of distilled and dried
pyridine without stirring. 68 g of phosphorus oxychloride were added dropwise
to this mixture under continual stirring. The temperature of the reactants,
initially at 20°C, was allowed to rise to about 60°C, and this temperature was
maintained for a further 60 minutes. Thereafter 24.5 g of meso-inositol wereadded gradually, the temperature being controlled so that it did not exceed
about 80°C. The reactants were maintained at this temperature for from 2 to
3 hours, and thereafter the reaction mixture was poured into 500 ml of water.
The pyridine salts formed during the reaction readily dissolved, and the mesoinositol hexanicotinate which had formed crystallized out. The ester was
filtered off and washed with water and acetone or alcohol. Finally, the mesoinositol hexanicotinate was dried at 100°C.
The yield was 90%, the melting point of the product was 258°C to 260°C. and
the chlorine content <0.01%.
brand name
Hexopal (Sterling Winthrop); Linodil (Sterling Winthrop); Palohex (Sterling Winthrop).
Therapeutic Function
Vasodilator
Clinical Use
Peripheral vascular disease
Hyperlipidaemia
Drug interactions
Potentially hazardous interactions with other drugs
Statins: increased risk of myopathy.
Metabolism
Inositol nicotinate is believed to be slowly hydrolysed
to nicotinic acid. The main route of metabolism is then
conversion to N-methylnicotinamide and the 2-pyridone
and 4-pyridone derivatives; nicotinuric acid is also
formed.
Small amounts of nicotinic acid are excreted unchanged
in urine.
Inositol nicotinate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Zelixir Biotech Co., Ltd. | +8618867646786 | neal.chen@zelixir.com | China | 230 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 1685 | 58 |
| Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 | clara@hbshengyang.com | China | 781 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15957 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1011 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
View Lastest Price from Inositol nicotinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-08 | Inositol nicotinate
6556-11-2
|
US $18.00-18.00 / kg | 1kg | 99.9 | 5000 | Hebei Shengyang Water Conservancy Engineering Co., Ltd. | |
 |
2024-05-07 | Inositol nicotinate
6556-11-2
|
US $35.00 / kg | 1kg | 99% | 5000kg/Week | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-04-12 | Inositol Nicotinate
6556-11-2
|
US $0.00 / kg | 1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd |
-
- Inositol nicotinate
6556-11-2
- US $18.00-18.00 / kg
- 99.9
- Hebei Shengyang Water Conservancy Engineering Co., Ltd.
-
- Inositol nicotinate
6556-11-2
- US $35.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Inositol Nicotinate
6556-11-2
- US $0.00 / kg
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd