1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE
- CAS No.
- 4430-35-7
- Chemical Name:
- 1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE
- Synonyms
- 6-MITC;6-HITC;6-MITC; 6 MITC; 6MITC;6-METHYLSULFINYLHEXYL ISOTHIOCYANATE;1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE;Hexane, 1-isothiocyanato-6-(methylsulfinyl)-
- CBNumber:
- CB4774237
- Molecular Formula:
- C8H15NOS2
- Molecular Weight:
- 205.34
- MDL Number:
- MFCD03093720
- MOL File:
- Mol file
| Boiling point | 385.9±25.0 °C(Predicted) |
|---|---|
| Density | 1.12±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator, under inert atmosphere |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Oil |
| color | Colourless to Pale Yellow |
| LogP | 0.959 (est) |
| FDA UNII | 8RUP6Q3JBB |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501 | |||||||||
| NFPA 704 |
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1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML3554 | 6-(Methylsulfinyl)hexyl isothiocyanate ≥98% (HPLC) | 4430-35-7 | 5MG | $81.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML3554 | 6-(Methylsulfinyl)hexyl isothiocyanate ≥98% (HPLC) | 4430-35-7 | 25MG | $327 | 2024-03-01 | Buy |
| Cayman Chemical | 19638 | 6-Methylsulfinylhexyl Isothiocyanate ≥98% | 4430-35-7 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 19638 | 6-Methylsulfinylhexyl Isothiocyanate ≥98% | 4430-35-7 | 5mg | $122 | 2024-03-01 | Buy |
| Cayman Chemical | 19638 | 6-Methylsulfinylhexyl Isothiocyanate ≥98% | 4430-35-7 | 10mg | $184 | 2024-03-01 | Buy |
1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE Chemical Properties,Uses,Production
Description
6-Methylsulfinylhexyl isothiocyanate (6-MSITC) is an isothiocyanate that has been found in wasabi (W. japonica) and has diverse biological activities. It inhibits nitric oxide (NO) production in mouse peritoneal exudate macrophages when used at a concentration of 5 μM. It inhibits aggregation of isolated human platelets induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607; IC50 = 21.9 μM). 6-MSITC reduces cell survival in a panel of breast, brain, colon, lung, ovarian, renal, and prostate cancer cell lines (mean IC50 = 43.7 μM). In vivo, 6-MSITC (5 mg/kg twice weekly) reduces apoptosis of substantia nigral dopaminergic neurons and motor dysfunction in a mouse model of Parkinson''s disease induced by 6-OHDA . 6-MSITC also reduces the number of lung metastases in a B16/F10 murine melanoma model.
Uses
6-(Methylsulfinyl)hexyl isothiocyanate derived from Wasabia japonica was discovered as an inhibitor of glycogen synthase kinase-3β.
Definition
ChEBI: 1-isothiocyanato-6-(methylsulfinyl)hexane is a sulfoxide.
1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE Preparation Products And Raw materials
Raw materials
Preparation Products
1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| YouCoChem (Beijing) Chemical Technology Co., Ltd. | 18800159827 | youcochem@163.com | China | 161 | 50 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9756 | 58 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-0755-85201366 18938635012 | sales@regentsciences.com | China | 9293 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55896 | 58 |