ChemicalBook >> CAS DataBase List >>BMS453
BMS453
- CAS No.
- 166977-43-1
- Chemical Name:
- BMS453
- Synonyms
- BMS453;BMS-189453 (BMS189453;(E)-4-[2-(5,5-Dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl]benzoic acid;(E)-4-[2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid;4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoicacid;Benzoic acid, 4-[(1E)-2-(5,6-dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-;Inhibitor,BMS453,retinoid,RAR/RXR,inhibit,BMS-453,BMS 189453,TGFβ,breast,RARβ,RARγ,Retinoid X receptors,BMS189453,arrest,cell,RARα,Retinoic acid receptors
- CBNumber:
- CB51387459
- Molecular Formula:
- C27H24O2
- Molecular Weight:
- 380.48
- MDL Number:
- MFCD18086870
- MOL File:
- 166977-43-1.mol
Last updated:2023-05-18 11:31:14
| Boiling point | 560.9±50.0 °C(Predicted) |
|---|---|
| Density | 1.167±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: soluble10mg/mL, clear |
| form | powder |
| pka | 4.27±0.10(Predicted) |
| color | white to beige |
| FDA UNII | M531IV9E0V |
BMS453 price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1149 | BMS-189453 ≥98% (HPLC) | 166977-43-1 | 5mg | $132 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1149 | BMS-189453 ≥98% (HPLC) | 166977-43-1 | 25mg | $535 | 2024-03-01 | Buy |
| Cayman Chemical | 19076 | BMS 453 ≥98% | 166977-43-1 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 19076 | BMS 453 ≥98% | 166977-43-1 | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 19076 | BMS 453 ≥98% | 166977-43-1 | 10mg | $178 | 2024-03-01 | Buy |
BMS453 Chemical Properties,Uses,Production
Uses
BMS 453 is a synthetic retinoid and RARβ antagonist which also displays antagonist acitivity in RARα.
Definition
ChEBI: BMS-453 is a member of the class of dihydronaphthalenes that is 1,2-dihydronaphthalene which is substituted at positions 1, 1, 4, and 6 by methyl, methyl, phenyl, and 2-(p-carboxyphenyl)vinyl groups, respectively (the E isomer). It is a potent retinoic acid receptor gamma (RARbeta) agonist that acts as an antagonist against RARalpha and RARgamma. It has a role as a retinoic acid receptor beta agonist, a retinoic acid receptor gamma antagonist, a retinoic acid receptor alpha antagonist and a teratogenic agent. It is a member of dihydronaphthalenes, a member of benzoic acids and a stilbenoid.
BMS453 Preparation Products And Raw materials
Raw materials
Preparation Products
BMS453 Suppliers
Global( 68)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 4664 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
BMS453
4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoicacid
(E)-4-[2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid
Benzoic acid, 4-[(1E)-2-(5,6-dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-
(E)-4-[2-(5,5-Dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl]benzoic acid
BMS-189453
(BMS189453
Inhibitor,BMS453,retinoid,RAR/RXR,inhibit,BMS-453,BMS 189453,TGFβ,breast,RARβ,RARγ,Retinoid X receptors,BMS189453,arrest,cell,RARα,Retinoic acid receptors
166977-43-1