ChemicalBook >> CAS DataBase List >>(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine_x000b_(Mixture of 2 Diastereomers)

(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine_x000b_(Mixture of 2 Diastereomers)

CAS No.
209414-26-6
Chemical Name:
(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine_x000b_(Mixture of 2 Diastereomers)
Synonyms
Efavirenz IP Imp J;Efavirenz Impurity J;Efavirenz IP Impurity J;Efavirenz Impurity 10(Efavirenz IP Impurity J);Efavirenz Impurity 13 (Mixture of Diastereomers);(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-Methoxyphenyl)-4-(trifluoroMethyl)-2H-3,1-benzoxazine;2H-3,1-Benzoxazine, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-, (4S)-;(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine (Mixture of 2 Diastereomers);(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine\n(Mixture of 2 Diastereomers)
CBNumber:
CB52486906
Molecular Formula:
C21H17ClF3NO2
Molecular Weight:
407.81
MDL Number:
MFCD16251295
MOL File:
209414-26-6.mol
Last updated:2023-04-23 13:52:06

(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine_x000b_(Mixture of 2 Diastereomers) Properties

Melting point 97-100°C
Boiling point 515.1±50.0 °C(Predicted)
Density 1.40±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility Methanol (Slightly)
form Solid
pka -0.71±0.60(Predicted)
color Off-White to Yellow
FDA UNII S40TCL042S

(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine_x000b_(Mixture of 2 Diastereomers) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C365140 (4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine(Mixtureof2Diastereomers) 209414-26-6 50mg $1190 2021-12-16 Buy
American Custom Chemicals Corporation HCH0069075 (4S)-6-CHLORO-4-(CYCLOPROPYLETHYNYL)-1,4-DIHYDRO-2-(4-METHOXYPHENYL)-4-(TRIFLUOROMETHYL)-2H-3,1-BENZOXAZINE 95.00% 209414-26-6 50MG $1963.5 2021-12-16 Buy
American Custom Chemicals Corporation HCH0069075 (4S)-6-CHLORO-4-(CYCLOPROPYLETHYNYL)-1,4-DIHYDRO-2-(4-METHOXYPHENYL)-4-(TRIFLUOROMETHYL)-2H-3,1-BENZOXAZINE 95.00% 209414-26-6 5MG $786.5 2021-12-16 Buy
Product number Packaging Price Buy
C365140 50mg $1190 Buy
HCH0069075 50MG $1963.5 Buy
HCH0069075 5MG $786.5 Buy

(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine_x000b_(Mixture of 2 Diastereomers) Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

An impurity arising in the synthesis of Efavirenz (E425000).

(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine_x000b_(Mixture of 2 Diastereomers) Preparation Products And Raw materials

Raw materials

Preparation Products

(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine_x000b_(Mixture of 2 Diastereomers) Suppliers

Global( 17)Suppliers
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Standardpharm Co. Ltd.
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CR Corporation Lomited
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J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8073 58
Shanghai CR Corporation Limited 4006653949 fred.wen@crcorporation.cn China 10108 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55896 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 17825480238 3008233717@qq.com China 9843 12
Jinan blalong chemical co. LTD 2710913286@.com 1513643261@qq.com China 14253 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8864 58
(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine (Mixture of 2 Diastereomers) (4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-Methoxyphenyl)-4-(trifluoroMethyl)-2H-3,1-benzoxazine Efavirenz Impurity 13 (Mixture of Diastereomers) Efavirenz IP Imp J Efavirenz Impurity 10(Efavirenz IP Impurity J) (4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-2H-3,1-benzoxazine\n(Mixture of 2 Diastereomers) Efavirenz IP Impurity J Efavirenz Impurity J 2H-3,1-Benzoxazine, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-2-(4-methoxyphenyl)-4-(trifluoromethyl)-, (4S)- 209414-26-6 Chiral Reagents Impurities Pharmaceuticals Chiral Reagents, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals Intermediates & Fine Chemicals