ChemicalBook >> CAS DataBase List >>GSK-3β Inhibitor XVIII
GSK-3β Inhibitor XVIII
- CAS No.
- 1139875-74-3
- Chemical Name:
- GSK-3β Inhibitor XVIII
- Synonyms
- GSK3β-IN-1a;GSK3β-IN-1a;GSK-3β inhibitor 8;GSK3β Inhibitor XVIII;GSK-3β Inhibitor XVIII;GSK-3β Inhibitor XVIII - CAS 1139875-74-3 - Calbiochem;2-chloro-4-[[4-(2-thienyl)-2-pyrimidinyl]amino]phenyl](4-methyl-1-piperazinyl)-,methanone;Methanone, [2-chloro-4-[[4-(2-thienyl)-2-pyrimidinyl]amino]phenyl](4-methyl-1-piperazinyl)-
- CBNumber:
- CB52602508
- Molecular Formula:
- C20H20ClN5OS
- Molecular Weight:
- 413.92
- MDL Number:
- MFCD32671859
- MOL File:
- 1139875-74-3.mol
Last updated:2023-05-18 11:31:20
GSK-3β Inhibitor XVIII price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 361562 | GSK-3β Inhibitor XVIII - CAS 1139875-74-3 - Calbiochem | 1139875-74-3 | 5mg | $238 | 2023-01-07 | Buy |
| Cayman Chemical | 21198 | GSK3β Inhibitor XVIII | 1139875-74-3 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 21198 | GSK3β Inhibitor XVIII | 1139875-74-3 | 5mg | $193 | 2024-03-01 | Buy |
| Cayman Chemical | 21198 | GSK3β Inhibitor XVIII | 1139875-74-3 | 10mg | $341 | 2024-03-01 | Buy |
| Cayman Chemical | 21198 | GSK3β Inhibitor XVIII | 1139875-74-3 | 25mg | $745 | 2024-03-01 | Buy |
GSK-3β Inhibitor XVIII Chemical Properties,Uses,Production
Description
GSK3β inhibitor XVIII is an inhibitor of glycogen synthase kinase 3β (GSK3β; IC50 = 64 nM). It induces expression of a luciferase reporter in HEK293 cells expressing wild-type Wnt (EC50 = ~1.25 μM) but not in cells expressing a β-catenin/TCF binding site-mutant Wnt. GSK3β inhibitor XVIII increases β-catenin accumulation in the nucleus of HEK293 cells. It induces proliferation of R7T1 β-cells (EC50 = 1,143 nM), an effect that can be blocked by the COX and Wnt signaling inhibitor sulindac , and rat primary β-cells.
GSK-3β Inhibitor XVIII Preparation Products And Raw materials
Raw materials
Preparation Products
GSK-3β Inhibitor XVIII Suppliers
Global( 16)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Nanjing Tengyi Biotechnology Co., Ltd | 025-58851786 17714337195 | sales@tybiochem.com | China | 5141 | 58 |
| Nantong Hanfang Biotechnology Co. , Ltd. | 3674309880 | hanfangpharma@126.com | China | 30968 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.com | China | 24246 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12007 | 58 |
1139875-74-3(GSK-3β Inhibitor XVIII)Related Search:
GSK-3β Inhibitor XVIII
GSK-3β Inhibitor XVIII - CAS 1139875-74-3 - Calbiochem
GSK3β-IN-1a
GSK3β Inhibitor XVIII
Methanone, [2-chloro-4-[[4-(2-thienyl)-2-pyrimidinyl]amino]phenyl](4-methyl-1-piperazinyl)-
GSK3β-IN-1a
2-chloro-4-[[4-(2-thienyl)-2-pyrimidinyl]amino]phenyl](4-methyl-1-piperazinyl)-,methanone
GSK-3β inhibitor 8
1139875-74-3