Intermediate of Rolapitant

Intermediate of Rolapitant structure

CAS No.: 205654-80-4

Chemical Name:: Intermediate of Rolapitant

Synonyms: Intermediate of Rolapitant;(2R,4S)-benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate;Benzyl (2r,4s)-5-oxo-2,4-diphenyloxazolidine-3-carboxylate;3-FLUORO-2-NITROPHENOL (2R)-5-OXOPYRROLIDINE-2-CARBOXYLIC ACID;3-Oxazolidinecarboxylic acid,5-oxo-2,4-diphenyl-,phenylmethyl ester,(2R,4S)-

CBNumber:: CB52743016

Molecular Formula:: C23H19NO4

Molecular Weight:: 373.4

MDL Number:: MFCD30718663

MOL File:: 205654-80-4.mol

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Intermediate of Rolapitant Properties

Boiling point	591.6±50.0 °C(Predicted)
Density	1.270±0.06 g/cm3(Predicted)
pka	-3.96±0.60(Predicted)

Intermediate of Rolapitant price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B287516	(2R,4S)-Benzyl5-oxo-2,4-diphenyloxazolidine-3-carboxylate	205654-80-4	2.5g	$990	2021-12-16	Buy

Product number	Packaging	Price	Buy
B287516	2.5g	$990	Buy

Intermediate of Rolapitant Chemical Properties,Uses,Production

Uses

(2R,4S)-Benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate is an intermediate in the preparation of Rolapitant (R639800). Rolapitant is an NK1 receptor antagonist that is used in the treatment of chemotherapy-induced nausea and vomiting.

Intermediate of Rolapitant Preparation Products And Raw materials

Raw materials

Preparation Products

Intermediate of Rolapitant Suppliers

Global( 7)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
AFINE CHEMICALS LIMITED	+86-0571-85134551	info@afinechem.com	China	15396	58
Shanghai QianYan Bio-technology Co., Ltd	02781293128	orders@biochemsafebuy.com	China	9934	55
Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd	+86-021-50929289 86186163093	sales@ypptech.com.cn	China	344	58
Suzhou Meishi Biotechnology Co., Ltd.	1173954148q	meishipharma@126.com	China	20035	58
Shaanxi Didu New Material Co., Ltd	029-63373950 15353716720	1052@dideu.com	China	10011	58
Suzhou Haiben Pharmaceutical Co., Ltd	14760821013 14760821013	1816280386@qq.com	China	8068	58
Shaanxi Henghan New Materials Co., Ltd	15719109892	907967238@qq.com	China	2572	58

Supplier	Advantage
AFINE CHEMICALS LIMITED	58
Shanghai QianYan Bio-technology Co., Ltd	55
Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd	58
Suzhou Meishi Biotechnology Co., Ltd.	58
Shaanxi Didu New Material Co., Ltd	58
Suzhou Haiben Pharmaceutical Co., Ltd	58
Shaanxi Henghan New Materials Co., Ltd	58

Intermediate of Rolapitant (2R,4S)-benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate 3-Oxazolidinecarboxylic acid,5-oxo-2,4-diphenyl-,phenylmethyl ester,(2R,4S)- 3-FLUORO-2-NITROPHENOL (2R)-5-OXOPYRROLIDINE-2-CARBOXYLIC ACID Benzyl (2r,4s)-5-oxo-2,4-diphenyloxazolidine-3-carboxylate 205654-80-4