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ML-180

ML-180 Structure
ML-180 structure
CAS No.
863588-32-3
Chemical Name:
ML-180
Synonyms
SR1848;ML-180;ML-180 (SR1848);SR1848 >=98% (HPLC);6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2，4-dione;6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione;6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine- ,4(1H,3H)dione;6-(4-(3-chlorophenyl)piperazin-1-yl)-3-cyclohexylpyrimidine-2,4(1H,3H)-dione;2,4(1H,3H)-Pyrimidinedione, 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-;6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CBNumber:
CB53152684
Molecular Formula:
C20H25ClN4O2
Molecular Weight:
388.89
MDL Number:
MFCD05894342
MOL File:
863588-32-3.mol
MSDS File:
SDS
Last updated:2023-09-20 16:43:00
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ML-180 Properties

Density 1.312±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 10 mg/ml
form A crystalline solid
pka 9.37±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
NFPA 704
0
2 0

ML-180 price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 15181 ML-180 ≥98% 863588-32-3 1mg $37 2024-03-01 Buy
Cayman Chemical 15181 ML-180 ≥98% 863588-32-3 5mg $108 2024-03-01 Buy
Cayman Chemical 15181 ML-180 ≥98% 863588-32-3 10mg $161 2024-03-01 Buy
Cayman Chemical 15181 ML-180 ≥98% 863588-32-3 25mg $345 2024-03-01 Buy
AK Scientific SYN5289 ML180 863588-32-3 10mg $160 2021-12-16 Buy
Product number Packaging Price Buy
15181 1mg $37 Buy
15181 5mg $108 Buy
15181 10mg $161 Buy
15181 25mg $345 Buy
SYN5289 10mg $160 Buy

ML-180 Chemical Properties,Uses,Production

Description

ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC50 = 3.7 μM) with maximum efficacy of 64% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the death of estrogen-receptor negative MDA-MB-231 breast cancer cells, and inhibits the steroidogenic acute regulatory promoter (IC50 = 2.05 μM).

Definition

ChEBI: 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione is a member of piperazines.

ML-180 Preparation Products And Raw materials

Raw materials

Preparation Products

ML-180 Suppliers

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		+86-18341751992 +86-15382112998 757984502@qq.com China 892 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 4664 58
Jingmo (Xiamen) Biotechnology Co., Ltd 13621943973 13515979683 sales@jamxmpharmatech.com China 1079 58
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4428 55
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4182 55
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		58
Aladdin Scientific 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
Jingmo (Xiamen) Biotechnology Co., Ltd 58
Guangzhou Isun Pharmaceutical Co., Ltd 55
Shanghai Lollane Biological Technology Co.,Ltd. 55

ML-180 Spectrum

ML-180(863588-32-3)1HNMR

863588-32-3(ML-180)Related Search:

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ML-180 SR1848 6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione 2,4(1H,3H)-Pyrimidinedione, 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl- 6-(4-(3-chlorophenyl)piperazin-1-yl)-3-cyclohexylpyrimidine-2,4(1H,3H)-dione SR1848 >=98% (HPLC) ML-180 (SR1848) 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine- ,4(1H,3H)dione 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione ML-180,steroidogenic,SR-1848,Inhibitor,ML180,Orphan,factor-1,LRH-1,cancers,nuclear,NR5A2,NR5A1,ML 180,inhibit,homolog,liver,SR 1848,receptor,SF-1 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2，4-dione 863588-32-3