Etofenamate
- CAS No.
- 30544-47-9
- Chemical Name:
- Etofenamate
- Synonyms
- ReuMon;TV-485;Rheumon;TVX-485;CS-1431;Bayrogel;Etofenate;Etofenamate;TrauMon Gel;Ethofenamate
- CBNumber:
- CB6883241
- Molecular Formula:
- C18H18F3NO4
- Molecular Weight:
- 369.33
- MDL Number:
- MFCD00242806
- MOL File:
- 30544-47-9.mol
- MSDS File:
- SDS
Melting point | 25°C |
---|---|
Boiling point | bp.001 130-135° |
Density | 1.2866 (estimate) |
refractive index | nD25 1.564 |
storage temp. | Sealed in dry,2-8°C |
solubility | Practically insoluble in water, miscible with ethanol (96 per cent) and with ethyl acetate. |
pka | 14.32±0.10(Predicted) |
Stability | Light Sensitive |
FDA UNII | KZF0XM66JC |
ATC code | M02AA06 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06,GHS09 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H301-H410 | |||||||||
Precautionary statements | P301+P330+P331+P310 | |||||||||
RIDADR | UN2810 - class 6.1 - PG 3 - EHS - Toxic, liquids, organic, n.o.s., HI: all | |||||||||
Toxicity | LD50 in male, female rats (mg/kg): 292, 470 orally; 140, 226 i.v.; 373, 397 i.p.; 643, 568 s.c. (Jacobi) | |||||||||
NFPA 704 |
|
Etofenamate price More Price(17)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | E2499901 | Etofenamate for peak identification European Pharmacopoeia (EP) Reference Standard | 30544-47-9 | e2499901 | $153 | 2024-03-01 | Buy |
Sigma-Aldrich | E2499900 | Etofenamate European Pharmacopoeia (EP) Reference Standard | 30544-47-9 | e2499900 | $150 | 2024-03-01 | Buy |
Cayman Chemical | 23674 | Etofenamate ≥98% | 30544-47-9 | 50mg | $89 | 2024-03-01 | Buy |
Cayman Chemical | 23674 | Etofenamate ≥98% | 30544-47-9 | 100mg | $141 | 2024-03-01 | Buy |
Cayman Chemical | 23674 | Etofenamate ≥98% | 30544-47-9 | 250mg | $264 | 2024-03-01 | Buy |
Etofenamate Chemical Properties,Uses,Production
Chemical Properties
Light Yellow Oil
Originator
Rheumon,Troponwerke,W. Germany,1977
Uses
As a histamine H1 -receptor antagonist, Etofenamate can be used as anti-inflammatory;cyclooxygenase inhibitor and medication used to alleviate joint and muscle pain.
Definition
ChEBI: 2-[3-(trifluoromethyl)anilino]benzoic acid 2-(2-hydroxyethoxy)ethyl ester is a benzoate ester.
Manufacturing Process
16.0 g (0.05 mol) of the potassium salt of N-(3-trifluoromethylphenyl)- anthranilic acid are dissolved in 60 ml of dimethylformamide and heated to 110°C, and 6.2 g (0.05 mol) of 2-(2-chloroethoxy)-ethanol are slowly added. The reaction mixture is then heated to boiling for 2 hours. The precipitated potassium chloride is filtered off and the solvent is removed by evaporation. The residue is separated over a column with 400 g of silica gel (particle size 0.05 to 0.2 mm), using a 1:1 mixture of cyclohexane and glacial acetic acid as eluting agent. 16.0 g of the 2-(2-hydroxyethoxy)-ethyl ester of N-(3- trifluoromethylphenyl)-anthranilic acid are obtained in the form of a pale yellow oil which does not crystallize and cannot be distilled.
Therapeutic Function
Antiinflammatory
Etofenamate Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 | 1056@dideu.com | China | 3131 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28149 | 58 |
AFINE CHEMICALS LIMITED | 0571-85134551 18958018566; | info@afinechem.com | China | 15377 | 58 |
View Lastest Price from Etofenamate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-07-20 | Etofenamate
30544-47-9
|
US $1.00-1.00 / KG | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd | ||
2021-06-10 | Etofenamate USP/EP/BP
30544-47-9
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | ||
2019-09-04 | Etofenamate
30544-47-9
|
US $5.00 / KG | 1KG | 99% | 1ton | Career Henan Chemical Co |
- Etofenamate
30544-47-9
- US $1.00-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
- Etofenamate USP/EP/BP
30544-47-9
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
- Etofenamate
30544-47-9
- US $5.00 / KG
- 99%
- Career Henan Chemical Co