ChemicalBook >> CAS DataBase List >>(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6 -dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-m ethyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexameth yl-1-oxacyclotetradecane-2,10-dione

(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6 -dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-m ethyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexameth yl-1-oxacyclotetradecane-2,10-dione

CAS No.
1675-02-1
Chemical Name:
(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6 -dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-m ethyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexameth yl-1-oxacyclotetradecane-2,10-dione
Synonyms
Erythromycin C - API;Erythromycin Impurity 6;Erythromycin Impurity 14;Erythromycin C (E1320000);3'-O-Demethylerythromycin;Erythromycin impurities 6;3"-O-DeMethylerythroMycin A;Erythromycin, 3''-O-demethyl-;Erythromycin C (Erythromycin Impurity 3);(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylaChemicalbookmino-3-hydroxy-6-methyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-
CBNumber:
CB71253972
Molecular Formula:
C36H65NO13
Molecular Weight:
719.9
MDL Number:
MFCD22666225
MOL File:
1675-02-1.mol
Last updated:2023-06-08 09:02:53

(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6 -dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-m ethyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexameth yl-1-oxacyclotetradecane-2,10-dione Properties

Melting point 121-125 °C
Boiling point 826.2±65.0 °C(Predicted)
Density 1.23±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble; Water: limited solubility
pka 13.09±0.70(Predicted)
FDA UNII 9X2R375YNZ

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
NFPA 704
0
2 0

(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6 -dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-m ethyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexameth yl-1-oxacyclotetradecane-2,10-dione price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E1320000 Erythromycin C European Pharmacopoeia (EP) Reference Standard 1675-02-1 e1320000 $220 2024-03-01 Buy
Sigma-Aldrich 1242021 Erythromycin C 1675-02-1 50mg $1600 2024-03-01 Buy
Cayman Chemical 23478 Erythromycin C ≥98% 1675-02-1 500μg $73 2024-03-01 Buy
Cayman Chemical 23478 Erythromycin C ≥98% 1675-02-1 1mg $138 2024-03-01 Buy
Cayman Chemical 23478 Erythromycin C ≥98% 1675-02-1 5mg $575 2024-03-01 Buy
Product number Packaging Price Buy
E1320000 e1320000 $220 Buy
1242021 50mg $1600 Buy
23478 500μg $73 Buy
23478 1mg $138 Buy
23478 5mg $575 Buy

(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6 -dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-m ethyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexameth yl-1-oxacyclotetradecane-2,10-dione Chemical Properties,Uses,Production

Description

Erythromycin C is an intermediate in the biosynthesis of erythromycin . It is also a potential impurity found in commercial preparations of erythromycin. Erythromycin C is half as active or less than erythromycin A or B against most Gram-positive and Gram-negative bacteria tested.

Uses

Erythromycin (E649950) impurity. A related substance in Erythromycin drug.

Uses

Erythromycin C (3’’-O-demethylerythromycin A) is a minor co-metabolite of erythromycin produced by Saccharopolyspora erythreae. Erythromycin C exhibits a narrower spectrum of antibiotic activity and is much less active than erythromycins A and B.

Definition

ChEBI: Erythromycin C is an erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively. It is functionally related to an erythronolide A. It is a conjugate base of an erythromycin C(1+).

(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6 -dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-m ethyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexameth yl-1-oxacyclotetradecane-2,10-dione Preparation Products And Raw materials

Raw materials

Preparation Products

(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6 -dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-m ethyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexameth yl-1-oxacyclotetradecane-2,10-dione Suppliers

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View Lastest Price from (3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6 -dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-m ethyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexameth yl-1-oxacyclotetradecane-2,10-dione manufacturers

(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6 -dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-m ethyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexameth yl-1-oxacyclotetradecane-2,10-dione 3'-O-Demethylerythromycin 3"-O-DeMethylerythroMycin A (3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylaChemicalbookmino-3-hydroxy-6-methyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy- Erythromycin C/(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-(((2R,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexa Erythromycin Impurity 14 Erythromycin Impurity 6 Erythromycin, 3''-O-demethyl- Erythromycin C (Erythromycin Impurity 3) Erythromycin C (E1320000) Erythromycin C - API Erythromycin impurities 6 1675-02-1 C36H65NO13 Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals