POPC
- CAS No.
- 26853-31-6
- Chemical Name:
- POPC
- Synonyms
- 1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;1-Palmitoyl-2-oleoyl-sn-glycero-3-PC;L-BETA-OLEOYL-GAMMA-PALMITOYL-ALPHA-LECITHIN;1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine;POPC;3-sn-Phospha;16:0-18:1 PC;2-oleoyl-1-palmitoyl;50-60% ALPHA, VINYL CARBONS);L-b-Oleoyl-g-palmitoyl-a-lecithin
- CBNumber:
- CB7328336
- Molecular Formula:
- C42H82NO8P
- Molecular Weight:
- 760.08
- MDL Number:
- MFCD00077387
- MOL File:
- 26853-31-6.mol
- MSDS File:
- SDS
| Melting point | -3 °C |
|---|---|
| storage temp. | -20°C |
| solubility | Ethanol: 25mg/ml |
| form | A crystalline solid |
| BRN | 4173237 |
| FDA UNII | TE895536Y5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H315-H319-H331-H336-H351-H361d-H372-H412 |
| Precautionary statements | P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| F | 1-8-10 |
POPC price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 42773 | 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine ≥99.0% (TLC) | 26853-31-6 | 100mg | $153 | 2024-03-01 | Buy |
| Sigma-Aldrich | 42773 | 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine ≥99.0% (TLC) | 26853-31-6 | 500mg | $454 | 2024-03-01 | Buy |
| Cayman Chemical | 15102 | 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC ≥98% | 26853-31-6 | 100mg | $76 | 2024-03-01 | Buy |
| Cayman Chemical | 15102 | 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC ≥98% | 26853-31-6 | 250mg | $179 | 2024-03-01 | Buy |
| Sigma-Aldrich | P3017 | 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine ≥95.5% (GC), ≥98% (TLC) | 26853-31-6 | 10mg | $215 | 2024-03-01 | Buy |
POPC Chemical Properties,Uses,Production
Description
1-
Description
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPhtCho), is a phosphatidylcholine, that belongs to a class of phospholipids that are a major component of biological membranes. This compound has been shown to decrease the expression of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor subunit GluR1 on the plasma membrane of CA1 region of rat hippocampal slices.
Uses
Glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.
Uses
16:0-18:1 PC has been used in the preparation of liposomes for the muramyl tripeptide encapsulation. It has also been used in the preparation of membrane scaffold protein 1 nanodisc. 16:0-18:1 PC may be used in the synthesis of discoidal reconstituted high-density lipoproteins.
Uses
The effect of non-ionic detergent on liposomes was studied with giant POPC liposomes. Increasing concentrations of detergent cause tubular protrusions, then indentations, to develop on spherical liposomes. At higher detergent concentrations, the liposomes burst.
Application
POPC is an important phospholipid for biophysical experiments and has been used to study various subjects such as lipid rafts. POPC is also used in systems mimicking the cell membrane such as Nanodiscs. It is available commercially synthetically and is naturally present in eukaryotic cell membranes.
Definition
ChEBI: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine is a phosphatidylcholine 34:1 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl) and 9Z-octadecenoyl (oleoyl) respectively. It has a role as a mouse metabolite. It is a phosphatidylcholine 34:1 and a 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine betaine. It is functionally related to a hexadecanoic acid and an oleic acid.
General Description
POPC is typically considered one of the model lipids for biophysical experiments. The fatty acid composition, i.e., saturated chain in the sn-1 position and unsaturated chain in the sn-2 position, mimics mammalian phospholipid composition. Since the major constituent in Egg PC is 1-palmitoyl-2-oleoyl PC, POPC is an excellent synthetic substitute for EPC.
Biochem/physiol Actions
1-palmitoyl-2-oleoyl-glycero-3-phosphocholine (POPC)or 16:0-18:1 PC plays an important role as a lung surfactant and reduces surface tension. POPC mimics natural cell membrane and may be useful for unsaturated lipids oxidation studies. Its interaction with ozone leads to oxidative decomposition at the oleoyl strand C-C moiety.
POPC Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12471 | 58 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
| Shochem(Shanghai) Co.,Ltd | 86-21-50800795 | info@shochem.com | CHINA | 288 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | 1015@dideu.com | China | 2263 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9635 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9335 | 58 |
View Lastest Price from POPC manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-10-16 | POPC
26853-31-6
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-09-06 | POPC
26853-31-6
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. | |
 |
2022-09-16 | POPC
26853-31-6
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. |
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