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6 beta-hydroxycortisol

CAS No.
53-35-0
Chemical Name:
6 beta-hydroxycortisol
Synonyms
NSC 76163;(6β,11β)-;Hydrocortisone IMpurity D;6-β-Hydroxy Hydrocortisone;6,17-Dihydroxycorticosterone;Hydrocortisone EP Impurity D;Hydrocortisone impurity D (EP);6beta,11beta,17,21-Tetrahydroxypreg;6,11,17a,21-Tetrahydroxypregn-4-en-3,20-dione;(6,11)-6,11,17,21-Tetrahydroxypregn-4-ene-3,20-dione
CBNumber:
CB91379726
Molecular Formula:
C21H30O6
Molecular Weight:
378.46
MDL Number:
MFCD00200405
MOL File:
53-35-0.mol
MSDS File:
SDS
Last updated:2023-05-15 10:43:56

6 beta-hydroxycortisol Properties

Melting point 182-190?C
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Pale Yellow
FDA UNII J37WKJ5Y50

6 beta-hydroxycortisol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC H922300 6β-HydroxyCortisol 53-35-0 25mg $1295 2021-12-16 Buy
American Custom Chemicals Corporation MTB0000599 6-BETA-HYDROXYCORTISOL 95.00% 53-35-0 5MG $501.02 2021-12-16 Buy
Labseeker SC-65652 6beta,11beta,17,21-Tetrahydroxypregn-4-ene-3,20-dione(6beta-Hydroxyhydrocortisone) 95 53-35-0 10g $1666 2021-12-16 Buy
Product number Packaging Price Buy
H922300 25mg $1295 Buy
MTB0000599 5MG $501.02 Buy
SC-65652 10g $1666 Buy

6 beta-hydroxycortisol Chemical Properties,Uses,Production

Chemical Properties

Off-White to Pale Yellow Solid

Uses

A metabolite of Cortisol

Definition

ChEBI: 6beta-hydroxycortisol is a C21-steroid that is cortisol bearing an additional hydroxy substituent at the 6beta-position. In humans, it is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo. It has a role as a mammalian metabolite, a human metabolite and a probe. It is a C21-steroid, a 6beta-hydroxy steroid, a 3-oxo-Delta(4) steroid, a 21-hydroxy steroid, a 20-oxo steroid, a 17alpha-hydroxy steroid, an 11beta-hydroxy steroid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It is functionally related to a cortisol.

6 beta-hydroxycortisol Preparation Products And Raw materials

Raw materials

Preparation Products

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(6β,11β)- Hydrocortisone IMpurity D (6R,8S,9S,10R,11S,13S,14S,17R)-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-diMethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one (6,11)-6,11,17,21-Tetrahydroxypregn-4-ene-3,20-dione 6,11,17a,21-Tetrahydroxypregn-4-en-3,20-dione 6,17-Dihydroxycorticosterone NSC 76163 Hydrocortisone impurity D (EP) Hydrocortisone EP Impurity D Hydrocortisone Impurity 4(Hydrocortisone EP Impurity D) 6beta,11beta,17,21-Tetrahydroxypreg Pregn-4-ene-3,20-dione, 6,11,17,21-tetrahydroxy-, (6β,11β)- Hydrocortisone EP Impurity D (6β-Hydroxycortisol/ 6β-Hydroxyhydrocortisone) 6-β-Hydroxy Hydrocortisone (6R,8S,9S,10R,11S,13S,14S,17R)-6,11,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one (Hydrocortisone Impurity) 53-35-0 Metabolites & Impurities Steroids Intermediates & Fine Chemicals Pharmaceuticals