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Eprazinone dihydrochloride

CAS No.
10402-53-6
Chemical Name:
Eprazinone dihydrochloride
Synonyms
746CE;Mucitux;Eftapan;Resplen;Rozuplen;NSC 317935;Eprazinone 2HCl;Eprazinone diHCl;EPRAZINONE HYDROCHLORIDE;Eprazinone 2hydrochloride
CBNumber:
CB9371811
Molecular Formula:
C24H33ClN2O2
Molecular Weight:
416.99
MDL Number:
MFCD01695215
MOL File:
10402-53-6.mol
Last updated:2023-06-08 09:02:59

Eprazinone dihydrochloride Properties

Melting point 201° (Toffel-Nadolny, Gielsdorf); mp 160° (Mauvernay)
storage temp. Sealed in dry,Room Temperature
solubility Methanol (Slightly), Water (Slightly)
form Solid
color White to Off-White
FDA UNII 394X1L8I9Y

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Toxicity LD50 in mice (mg/kg): 729 orally, 38 i.v. (Vacher)
NFPA 704
0
2 0

Eprazinone dihydrochloride price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 448353 Eprazinone Dihydrochloride 10402-53-6 50mg $355 2021-12-16 Buy
TRC E590020 EprazinoneDihydrochloride 10402-53-6 250mg $215 2021-12-16 Buy
ChemScene CS-0019683 Eprazinonedihydrochloride 10402-53-6 250mg $225 2021-12-16 Buy
Medical Isotopes, Inc. 94335 Eprazinone Dihydrochloride 10402-53-6 50mg $375 2021-12-16 Buy
ChemScene CS-0019683 Eprazinonedihydrochloride 10402-53-6 500mg $380 2021-12-16 Buy
Product number Packaging Price Buy
448353 50mg $355 Buy
E590020 250mg $215 Buy
CS-0019683 250mg $225 Buy
94335 50mg $375 Buy
CS-0019683 500mg $380 Buy

Eprazinone dihydrochloride Chemical Properties,Uses,Production

Originator

Mucitux,Riom,France,1969

Uses

Eprazinone Dihydrochloride is a drug used to improve pulmonary function in patients with chronic bronchitis.

Definition

ChEBI: A hydrochloride obtained by combining eprazinone with two molar equivalents of hydrochloric acid.

Manufacturing Process

61.4 g of 0.2M of 1-(2-phenyl-2-ethoxy)piperazine dihydrochloride, 33.5 g (0.25M) propiophenone, 75 g (0.25M) trioxymethylene, 120 ml of ethanol and 0.4 ml of concentrated HCl are heated under reflux for 4 to 5 hours. The product is allowed to crystallize, then filtered and washed with alcohol. It is dried and recrystallized from methanol containing 10% H2O.
There is thus obtained 60 g of a white crystalline powder soluble in water. Yield: 66%. Melting point: 160°C.

Therapeutic Function

Antitussive

Eprazinone dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Eprazinone dihydrochloride Suppliers

Global( 116)Suppliers
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Eprazinone dihydrochloride Spectrum

EPRAZINONE HYDROCHLORIDE 3-[4-(beta-ethoxyphenethyl)-1-piperazinyl]-2-methylpropiophenone dihydrochloride 1-Propanone, 3-[4-(2-ethoxy-2-phenylethyl)-1-piperazinyl]-2-methyl-1-phenyl-, dihydrochloride 746CE Eftapan Mucitux NSC 317935 Propiophenone, 3-[4-(β-ethoxyphenethyl)-1-piperazinyl]-2-methyl-, dihydrochloride (8CI) Resplen 1-(2-Benzoylpropyl)-4-(2-ethoxy-2-phenylethyl)piperazine dihydrochloride Eprazinone 2HCl 1-Propanone, 3-[4-(2-ethoxy-2-phenylethyl)-1-piperazinyl]-2-methyl-1-phenyl-, hydrochloride (1:2) 3-[4-(2-Ethoxy-2-phenylethyl)piperazin-1-yl]-2-methyl-1-phenylpropan-1-one dihydrochloride Eprazinone dihydrochloride Rozuplen Eprazinone diHCl 3-[4-(β-ethoxyphenethyl)-1-piperazinyl]-2-Methylpropiophenone dihydrochloride Eprazinone 2hydrochloride -2-methyl-1-phenylpropan-1-one dihydrochloride 3-(4-(2-Ethoxy-2-phenylethyl) 3-[4-(β-ethoxyphenethyl)-1-piperazinyl]-2-methylpropiopheno... Eprazinone DihydrochlorideQ: What is Eprazinone Dihydrochloride Q: What is the CAS Number of Eprazinone Dihydrochloride Q: What is the storage condition of Eprazinone Dihydrochloride Q: What are the applications of Eprazinone Dihydrochloride 10402-53-6 C24H32N2O22HCl C24H34N2O2Cl2 C24H34Cl2N2O2 Inhibitors