ビエタミベリン 化学特性,用途語,生産方法
Originator
Bietamiverine,Shanghai Lansheng Corporation
Manufacturing Process
To a solution of 117 g of diethylaminoethanol in 1000 ml of benzene was
added a solution of 94.5 g phenylchloroacetic acid in 400 ml benzene (time of
addition 1 hour). Then the reaction mixture was refluxed for 2 hours. To the
obtained solution was added an aqueous solution of sodium carbonate. Then
to the solution which was dried with sodium sulfate was added 85 g of
piperidine and the solution was refluxed for 2 hours. The obtained solution
was washed with water, dried with sodium sulfate and distilled. Yield of α-
phenyl-1-piperidineacetic acid 2-diethylaminoethyl ester 115 g, Kp1 180°C.
Therapeutic Function
Spasmolytic
ビエタミベリン 上流と下流の製品情報
原材料
準備製品