2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate
2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate 物理性質
- 沸点 :
- 253℃
- 比重(密度) :
- 1.172
- 闪点 :
- 107℃
安全性情報
2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate 価格
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2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate 化学特性,用途語,生産方法
使用
2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate is used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
合成
The reaction was carried out under a nitrogen atmosphere. TBS- ethylene glycol prepared as per step 1 (85.10g, 0.48 mol) and 2, 6-Lutidine (84.28ml, 0.72 mol) were stirred in n-heptane (425ml) to give a clear solution which was then cooled to -15 to - 25°C. Trifluoromethanesulfonic anhydride (Tf2O) (99.74 ml, 0.590 mol) was added drop-wise over a period of 45 minutes to the n-heptane solution (white precipitate starts to form immediately) while maintaining the reaction at -15 to -25°C. The reaction mixture was kept at temperature between -15 to -25°C for 2 hours. The precipitate generated was filtered off. The filtrate was then evaporated up to ~2 volumes with respect to TBS-ethyiene glycol (~200 ml).
2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate 上流と下流の製品情報
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2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate 生産企業
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164162-36-1()キーワード:
- 164162-36-1
- Trifluoromethanesulfonic acid 2-[[(tert-butyl)dimethylsilyl]oxy]ethyl ester
- 2-(t-ButyldiMethylsilyl)oxyethyl triflate
- Methanesulfonicacid,1,1,1-trifluoro-,2-[[(1,1-diMethylethyl)diMethylsilyl]oxy]ethylester
- 2-(t-Butyldimethylsilyloxy)EthylTrifluoromethanesulfonate
- 2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate
- 2-(tert-butyldiMethylsilyloxy)ethyl trifluoroMethanesulfonate
- 1,1,1-Trifluoromethanesulfonic acid 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl ester
- 2-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}ethyl trifluoromethanesulfonate
- Everolimus Impurity 12
- 2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]ethyl 1,1,1-trifluoromethanesulfonate
- Everolimus intermediate A2(Z)
- 2-(tert-Butydilethylsily) oxyethyl
- 2-(tert-Butyldimethylsilyloxy)ethyl triflate