1-PALMITYLTHIO-2-PALMITOYLAMIDO-1,2-DIDEOXY-SN-GLYCERO-3-PHOSPHOCHOLINE 化学特性,用途語,生産方法
説明
Thioetheramide-
PC is a structurally modified phospholipid that functions as a competitive, reversible inhibitor of secretory phospholipase A
2 (sPLA
2). The IC
50 value for thioetheramide-
PC is 2 μM at a substrate concentration of 0.5 mM. In addition to binding to the catalytic site of sPLA
2, thioetheramide-
PC also binds to the activator site of this enzyme. The binding of thioetheramide-
PC to the activator site is tighter than its binding to the catalytic site. The result of this dual interaction is that at low concentrations thioetheramide-
PC may activate phospholipase activity rather than inhibiting it.
1-PALMITYLTHIO-2-PALMITOYLAMIDO-1,2-DIDEOXY-SN-GLYCERO-3-PHOSPHOCHOLINE 上流と下流の製品情報
原材料
準備製品