O-アセチルクエン酸 トリエチル 化学特性,用途語,生産方法
外観
無色～ほとんど無色透明液体
定義
本品は、アセチル化したクエン酸(*)とエタノール(*)とのトリエステルであり、次の化学式で表される。
参照表示名称：クエン酸, エタノール
化粧品の成分用途
可塑剤、香料
化学的特性
Acetyltriethyl citrate occurs as a clear, odorless, practically colorless
oily liquid.
使用
ATEC is produced by the reaction of citric acid triethyl ester
with acetic acid anhydride. It is used as a solvent plasticizer
for cellulose nitrate and cellulose acetate.
調製方法
Acetyltriethyl citrate is prepared by the esterification of citric acid
with ethanol followed by acylation with acetic anhydride.
定義
Aqueous-based pharmaceutical coat-
ings.
一般的な説明
Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Triethyl 2-acetylcitrate is widely used in hydrophilic adhesives for medications and in biodegradable composition for papermaking and nonwoven production.
応用例（製薬）
Acetyltriethyl citrate is used to plasticize polymers in formulated
pharmaceutical coatings. The coating applications include
capsules, tablets, beads and granules for taste masking, immediate
release, sustained-release and enteric formulations. It is also
used in diffusion-controlled release drug delivery systems.
安全性
Acetyltriethyl citrate is used in oral pharmaceutical formulations
and is generally regarded as a nontoxic and nonirritating material.
However, ingestion of large quantities may be harmful.
LD
50 (cat, oral): 8.5 g/kg
LD
50 (mouse, IP): 1.15 g/kg
LD
50 (rat, oral): 7 g/kg
貯蔵
Acetyltriethyl citrate should be stored in dry, closed containers at
temperatures not exceeding 388℃. When stored in accordance with
these conditions, acetyltriethyl citrate is a stable product.
不和合性
Acetyltriethyl citrate is incompatible with strong alkalis and
oxidizing materials.
規制状況(Regulatory Status)
Approved in the USA for direct food contact in food films.
O-アセチルクエン酸 トリエチル 上流と下流の製品情報
原材料
準備製品