Ofloxacin manufacturers and suppliers

Ofloxacin suppliers

Properties

Melting point:: 270-2750C

Boiling point:: 571.5±50.0 °C(Predicted)

Density: 1.2688 (estimate)

storage temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C

solubility: 1 M NaOH: soluble50mg/mL

pka: 5.19±0.40(Predicted)

color: Colorless needles from ethanol

Water Solubility: Soluble in acetic acid or water. Slightly soluble in methanol

λmax: 326nm(H2O)(lit.)

Merck: 14,6771

BCS Class: 1

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H303

Precautionary statements: P270-P301+P312-P403-P501c

Hazard Codes: Xn,Xi

Risk Statements: 22-42/43-68-36/37/38

Safety Statements: 26-36/37/39-24/25-22-37/39-60

WGK Germany: 3

RTECS: UU8815550

HS Code: 29349990

Toxicity: LD50 in male, female mice, male, female rats (mg/kg): 5450, 5290, 3590, 3750 orally; 208, 233, 273, 276 i.v.; >10000, >10000, 7070, 9000 s.c. (Ohno)

Use

Ofloxacin is a fluoroquinolone antibiotic present as a racemic mixture. Levofloxacin, S-isomer of ofloxacin, shows a broad spectrum of antibacterial activity against both gram-positive and gram-negative bacteria. The antibacterial activity of levofloxacin is 8–128 times greater than that of the corresponding R-isomer. A novel esterase of type B1 carboxylesterase/lipase family from a marine isolate Y. lipolytica CL180 was used to resolve a racemic mixture of ofloxacin ester. This esterase showed an enantioselectivity toward R, S-ofloxacin ester, and levofloxacin was produced with an enantiomeric excess of 52 % (Kim et al. 2007).

You can find Ofloxacin suppliers, manufacturers, and distributors from countries such as CHINA, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.