Ceftriaxone sodium suppliers
Ceftriaxone Sodium
- CAS:
- 74578-69-1
- MF:
- C18H19N8NaO7S3
- MW:
- 578.57
Suppliers by country/region
Company Type
Properties
- storage temp.
- 4°C, protect from light
- solubility
- Soluble in DMSO (50 mM)
- color
- White to off-white
- Water Solubility
- Water : ≥ 40 mg/mL (66.60 mM)
- InChIKey
- CDCJSJLFRBHEHN-ZZKDXJNYNA-N
- SMILES
- C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC)C(=O)N12)CSC1=NC(=O)C(=O)NN1C)(=O)O.[NaH] |&1:5,7,r|
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Danger
- Hazard statements
- H334-H317
- Precautionary statements
- P261-P285-P304+P341-P342+P311-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
Use
Ceftriaxone sodium is antibacteria. Ceftriaxone sodium is a β-lactamase–resistantcephalosporin with an extremely long serum half-life.Once-daily dosing suffices for most indications. Two factorscontribute to the prolonged duration of action ofceftriaxone: high protein binding in the plasma and slowurinary excretion. Ceftriaxone is excreted in both the bileand the urine. Its urinary excretion is not affected byprobenecid. Despite its comparatively low volume ofdistribution, it reaches the cerebrospinal fluid in concentrationsthat are effective in meningitis. Nonlinear pharmacokineticsare observed. Ceftriaxone contains a highly acidic heterocyclic systemon the 3-thiomethyl group. This unusual dioxotriazine ringsystem is believed to confer the unique pharmacokineticproperties of this agent. Ceftriaxone has been associatedwith sonographically detected “sludge,” or pseudolithiasis,in the gallbladder and common bile duct. Symptoms ofcholecystitis may occur in susceptible patients, especiallythose on prolonged or high-dose ceftriaxone therapy. Theculprit has been identified as the calcium chelate. Ceftriaxone exhibits excellent broad-spectrum antibacterialactivity against both Gram-positive and Gram-negativeorganisms. It is highly resistant to most chromosomally andplasmid-mediated β-lactamases. The activity of ceftriaxoneagainst Enterobacter, Citrobacter, Serratia, indole-positiveProteus, and Pseudomonas spp. is particularly impressive. Itis also effective in the treatment of ampicillin-resistant gonorrheaand H. influenzae infections but generally less activethan cefotaxime against Gram-positive bacteria and B.fragilis.
295 supplier list of "Ceftriaxone Sodium"
$1.00/ 1PCS
- Product Name:Ceftriaxone sodium
- Products Intro:Purity: 99%|Package: 1PCS;1USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: DHA,4'-Methylpropiophenone,Procaine hcl,tetramisole hcl,lidocaine
$0.00/ 25KG
- Product Name:Ceftriaxone sodium
- Products Intro:Purity: 99%|Package: 25KG;0.00;USD
- Company Type: Service provider
- Country/Region: CHINA
- Main Products: carbomer,lead acetate,phenylacetamide,Xylazine,Xylazine hcl
$10.00/ 1KG
- Product Name:Ceftriaxone sodium
- Products Intro:Purity: 99% | Package: 1KG;10USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Iron Sucrose,Doxofylline,Clindamycin hydrochloride,3-Buten-1-ol,3-Methylaminopropionitrile
$0.00/ 1KG
- Product Name:Ceftriaxone Sodium
- Products Intro:Purity: 99% | Package: 1KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Ceftriaxone sodium
- Products Intro:Purity: 99.912% | Package: 1kg;15USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Sodium lignosulfonate,phenylglycine,5337-93-9,141-78-6,Dispersant MF
$1.00/ 1kg
- Product Name:Ceftriaxone sodium
- Products Intro:Purity: 99% | Package: 1kg;1USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information