Dipyridamole manufacturers and suppliers

Dipyridamole suppliers

Properties

Melting point:: 165-166 °C (lit.)

Boiling point:: 593.96°C (rough estimate)

Density: 1.2046 (rough estimate)

refractive index: 1.6910 (estimate)

storage temp.: room temp

solubility: DMSO: soluble

form: powder

pka: pKa 6.4 (Uncertain)

color: yellow

Water Solubility: Soluble in chloroform, methanol, dilute acids, ethanol. Slightly soluble in water.

Merck: 14,3346

Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319-H335

Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes: Xi

Risk Statements: 36/37/38

Safety Statements: 26-36

WGK Germany: 2

RTECS: KK7450000

HS Code: 29335990

Toxicity: LD50 in rats: 8.4 g/kg orally; 208 mg/kg i.v. (Takenaka)

Use

Dipyridamole, 2,2',2',2'''-[(4,8-di-1piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]-tetrakisethanol (Persantine), may be used for coronary andmyocardial insufficiency. Its biggest use today, however, isas an antithrombotic in patients with prosthetic heart valves.It is a bitter, yellow, crystalline powder, soluble in diluteacids, methanol, or chloroform. A formulation containingdipyridamole and aspirin (Aggrenox) is currently beingmarketed as an antithromobotic.Dipyridamole is a long-acting vasodilator. Its vasodilatingaction is selective for the coronary system; it is indicatedfor long-term therapy of chronic angina pectoris. Thedrug also inhibits adenosine deaminase in erythrocytesand interferes with the uptake of the vasodilator adenosineby erythrocytes. These actions potentiate the effect ofprostacyclin (PGI2), which acts as an inhibitor to plateletaggregation.

You can find Dipyridamole suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.