Loratadine suppliers
Loratadine
- CAS:
- 79794-75-5
- MF:
- C22H23ClN2O2
- MW:
- 382.88
Suppliers by country/region
- China(310)
- Singapore(2)
- United States(66)
- United Kingdom(22)
- India(154)
- Canada(10)
- Germany(8)
- Switzerland(3)
- Europe(2)
- Spain(8)
- The Netherlands(2)
- France(5)
- Brazil(5)
- Mexico(2)
- Nepal(1)
- Jordan(1)
- Italy(1)
- Iran(1)
- Malaysia(1)
- United Arab Emirates(1)
- Slovenia(1)
- Colombia(1)
- Austria(2)
- South Korea(2)
- Japan(1)
- Belgium(2)
- Indonesia(1)
- Greece(1)
Company Type
Properties
- Melting point:
- 134-136°C
- Boiling point:
- 531.3±50.0 °C(Predicted)
- Density
- 1.261±0.06 g/cm3(Predicted)
- RTECS
- TM6129200
- storage temp.
- 2-8°C
- solubility
- DMSO: 26 mg/mL, soluble
- form
- powder
- pka
- 4.27±0.20(Predicted)
- color
- white
- Water Solubility
- It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol.
- Merck
- 14,5578
- BCS Class
- 2
- Stability:
- Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents.
- InChIKey
- JCCNYMKQOSZNPW-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H319-H335-H315
- Precautionary statements
- P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-24/25-36-26
- RIDADR
- 3077
- WGK Germany
- 2
- HS Code
- 29333990
Use
Loratadine, 4-(8-chloro-5,6-dihydro-11Hbenzo[5,6]-cyclohepta[1,2-b]pyridin-l 1-ylidene-1-carboxylic acid ethyl ester, is a white to off-white powder insoluble in water but very soluble in acetone, alcohols, and chloroform. Loratadine is structurally related to the antihistamines azatadine and cyproheptadine, and to some tricyclic antidepressants. It differs from azatadine, in that a neutral carbamate group has replaced the basic tertiary amino moiety, and a phenyl ring has been substituted with a chlorine atom. Loratadine is a selective peripheral H1-antihistamine with a receptor-binding profile like that of the other members of this series, except that it has more antiserotonergic activity. Thus, it produces no substantial CNS or autonomic side effects or cardiac toxicity. Loratadine displays potency comparable with that of astemizole and greater than that of terfenadine. Loratadine is indicated for the relief of nasal and nonnasal symptoms of seasonal allergic rhinitis. In the presence of a CYP3A4 inhibitor ketoconazole, loratadine is metabolized to descarboethoxyloratadine predominantly by CYP2D6.
633 supplier list of "Loratadine"
$0.00-0.00 / 1Kg
- Product Name:Loratadine
- Products Intro:Purity: 99.9%|Package: 1Kg;0.00;USD|5Kg;0.00;USD|25Kg;0.00;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: organic chemical,inorganic chemical,Organic intermediates
$0.00-0.00 / 1Kg/Bag
- Product Name:Loratadine
- Products Intro:Purity: 0.99 | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: APIs,pharmaceutical intermediates,health and food supplements,cosmetic raw materials,herbal extracts
$0.00/ 25KG
- Product Name:Loratadine
- Products Intro:Purity: 99% | Package: 25KG
- Company Type: Service provider
- Country/Region: CHINA
- Main Products: carbomer,lead acetate,phenylacetamide,Xylazine,Xylazine hcl
$0.00-0.00 / 1Kg
- Product Name:Loratadine
- Products Intro:Purity: 99% | Package: 1Kg;|5Kg;|25Kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 5-bromo-1h-indazole-3-carboxylic acid,1,1′-(Azodicarbonyl)dipiperidine,2,4-Difluorobenzaldehyde,1H-Indazole-3-acetic acid,5-Bromo-1H-indazole-3-acetic acid
- Product Name:Loratadine
- Products Intro:Purity: 99.8% | Package: 1kg;45USD|25kg;40USD|100kg;35USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 5449-12-7,28578-16-7,Semaglutide,Tirzepatide,BDO
$30.00/ 1kg
- Product Name:Loratadine
- Products Intro:Purity: 98% | Package: 1kg;30USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: slimming peptide,Antiwrinkle peptide,Titanium for fitness,Semaglutide
$0.00/ 1kg
- Product Name:Loratadine
- Products Intro:Purity: 99% | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA