Thioridazine hydrochloride manufacturers and suppliers

Thioridazine hydrochloride suppliers

Properties

Melting point:: 158-1600C

Boiling point:: 230°C (rough estimate)

Density: 1.1227 (rough estimate)

refractive index: 1.5610 (estimate)

storage temp.: 2-8°C

solubility: H2O: soluble250 mg plus 5 ml of solvent, clear, colorless to faintly yellow

form: Off-white solid

color: White to Almost white

Water Solubility: Soluble in water (75 mM), DMSO (100 mM), chloroform, ethanol, and methanol.

Sensitive: Light Sensitive & Hygroscopic

λmax: 317nm(EtOH)(lit.)

Merck: 14,9359

InChIKey: NZFNXWQNBYZDAQ-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P264-P270-P301+P312-P501

Hazard Codes: Xn,N

Risk Statements: 22-36/37/38-50/53

Safety Statements: 26-36-60-61

RIDADR: UN 3077 9/PG 3

WGK Germany: 3

RTECS: SP2275000

HazardClass: 9

HS Code: 2934302300

Use

Thioridazine hydrochloride,10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine monohydrochloride (Mellaril), is amember of the piperidine subgroup of the phenothiazines.The drug has a relatively low tendency to produce EPS. Thedrug has high anticholinergic activity, and this activity in thestriatum, counterbalancing a striatal DA block, may be responsiblefor the low EPS. It also has been suggested thatthere may be increased DA receptor selectivity, which may be responsible. The drug has sedative and hypotensive activityin common with chlorpromazine and less antiemeticactivity. At high doses, pigmentary retinopathy has been observed.Its major metabolites include N-demethylated, ringhydroxylated,and S-oxidized products. Thioridazine isprominently converted to the active metabolite mesoridazine(discussed next), which probably contributes to the antipsychoticactivity of thioridazine.

You can find Thioridazine hydrochloride suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.