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ChemicalBook >> CAS DataBase List >> N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)Methyl)piperazine-1-carboxaMide

N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)Methyl)piperazine-1-carboxaMide

N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)Methyl)piperazine-1-carboxaMide price.
  • $44 - $1125
  • Product name: N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)Methyl)piperazine-1-carboxaMide
  • CAS: 1346528-50-4
  • MF: C18H17ClF2N4O3
  • MW: 410.8
  • EINECS:-0
  • MDL Number:MFCD29047142
  • Synonyms:N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)Methyl)piperazine-1-carboxaMide;N-(4-Chloro-3-pyridinyl)-4-[(2,2-difluoro-1,3-benzodioxol-5-yl)methyl]-1-piperazinecarboxamide;JNJ42165279;CS-2830;JNJ 42165279;JNJ42165279;1-Piperazinecarboxamide, N-(4-chloro-3-pyridinyl)-4-[(2,2-difluoro-1,3-benzodioxol-5-yl)methyl]-;JNJ-42165279 (JNJ-5279);Fatty acid amide hydrolase,inhibit,Autophagy,JNJ 42165279,FAAH,JNJ-42165279,Inhibitor
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  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
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  • ManufacturerAK Scientific
  • Product number7849DL
  • Product descriptionN-(4-Chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methyl)piperazine-1-carboxamide
  • Packaging5mg
  • Price$289
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberC4122
  • Product descriptionJNJ-42165279
  • Packaging10mg
  • Price$291
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberC4122
  • Product descriptionJNJ-42165279
  • Packaging25mg
  • Price$546
  • Updated2021-12-16
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  • ManufacturerCayman Chemical
  • Product number19987
  • Product descriptionJNJ-42165279 ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number19987
  • Product descriptionJNJ-42165279 ≥98%
  • Packaging5mg
  • Price$172
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number19987
  • Product descriptionJNJ-42165279 ≥98%
  • Packaging10mg
  • Price$257
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number19987
  • Product descriptionJNJ-42165279 ≥98%
  • Packaging25mg
  • Price$479
  • Updated2024-03-01
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  • ManufacturerChemenu
  • Product numberCM161405
  • Product descriptionN-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methyl)piperazine-1-carboxamide 95%+
  • Packaging100mg
  • Price$888
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-5411
  • Product descriptionJNJ-42165279 99.97%
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-5411
  • Product descriptionJNJ-42165279 99.97%
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-5411
  • Product descriptionJNJ-42165279 99.97%
  • Packaging25mg
  • Price$350
  • Updated2021-12-16
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  • ManufacturerCrysdot
  • Product numberCD31003801
  • Product descriptionJNJ-42165279 98+%
  • Packaging10mg
  • Price$273
  • Updated2021-12-16
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  • ManufacturerCrysdot
  • Product numberCD31003801
  • Product descriptionJNJ-42165279 98+%
  • Packaging25mg
  • Price$481
  • Updated2021-12-16
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  • ManufacturerCrysdot
  • Product numberCD31003801
  • Product descriptionJNJ-42165279 98+%
  • Packaging50mg
  • Price$818
  • Updated2021-12-16
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  • ManufacturerCrysdot
  • Product numberCD31003801
  • Product descriptionJNJ-42165279 98+%
  • Packaging100mg
  • Price$1125
  • Updated2021-12-16
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  • ManufacturerDC Chemicals
  • Product numberDC9662
  • Product descriptionJNJ-42165279 >98%
  • Packaging250mg
  • Price$1100
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7849DL N-(4-Chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methyl)piperazine-1-carboxamide 5mg $289 2021-12-16 Buy
ApexBio Technology C4122 JNJ-42165279 10mg $291 2021-12-16 Buy
ApexBio Technology C4122 JNJ-42165279 25mg $546 2021-12-16 Buy
Cayman Chemical 19987 JNJ-42165279 ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 19987 JNJ-42165279 ≥98% 5mg $172 2024-03-01 Buy
Cayman Chemical 19987 JNJ-42165279 ≥98% 10mg $257 2024-03-01 Buy
Cayman Chemical 19987 JNJ-42165279 ≥98% 25mg $479 2024-03-01 Buy
Chemenu CM161405 N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methyl)piperazine-1-carboxamide 95%+ 100mg $888 2021-12-16 Buy
ChemScene CS-5411 JNJ-42165279 99.97% 5mg $120 2021-12-16 Buy
ChemScene CS-5411 JNJ-42165279 99.97% 10mg $180 2021-12-16 Buy
ChemScene CS-5411 JNJ-42165279 99.97% 25mg $350 2021-12-16 Buy
Crysdot CD31003801 JNJ-42165279 98+% 10mg $273 2021-12-16 Buy
Crysdot CD31003801 JNJ-42165279 98+% 25mg $481 2021-12-16 Buy
Crysdot CD31003801 JNJ-42165279 98+% 50mg $818 2021-12-16 Buy
Crysdot CD31003801 JNJ-42165279 98+% 100mg $1125 2021-12-16 Buy
DC Chemicals DC9662 JNJ-42165279 >98% 250mg $1100 2021-12-16 Buy

Properties

Boiling point :541.2±50.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
form :crystalline solid
pka :12.91±0.20(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

JNJ-42165279 is a potent, irreversible inhibitor of fatty acid amide hydrolase (FAAH; IC50s = 70 and 313 nM for human and rat forms, respectively). It displays selectivity for FAAH over a panel of other enzymes, receptors, transporters, and ion channels. JNJ-42165279 is active in vivo, blocking FAAH activity in brain and periphery of rats and raising concentrations of anandamide , oleoyl ethanolamide , and palmitoyl ethanolamide . It is also efficacious in the spinal nerve ligation model of neuropathic pain.