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ChemicalBook >> CAS DataBase List >> 4-(Trifluoromethyl)nicotinic acid

4-(Trifluoromethyl)nicotinic acid

4-(Trifluoromethyl)nicotinic acid price.
  • $5 - $1819.8
  • Product name: 4-(Trifluoromethyl)nicotinic acid
  • CAS: 158063-66-2
  • MF: C7H4F3NO2
  • MW: 191.11
  • EINECS:623-902-1
  • MDL Number:MFCD00082626
  • Synonyms:4-(Trifluoromethyl)pyridine-3-carboxylic acid, 3-Carboxy-4-(trifluoromethyl)pyridine;FlonicaMide Metabolite (TFNA type, 4-TriuoroMethyl nicotinic acid);4-(TrifluoroMethyl)-3-Pyridinecarboxylic Acid;3-Pyridinecarboxylic acid, 4-(trifluoromethyl)-;4-(Trifluoromethyl)pyridine-3-carboxylic acid 98%;4-(Trifluoromethyl)pyridine-3-carboxylic acid, >=98%;4-(TRIFLUOROMETHYL)NICOTINIC ACID;BUTTPARK 43\57-42
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  • 1gm:
  • ManufacturerAHH
  • Product numberMT-40378
  • Product description4-(Trifluoromethyl)nicotinic Acid 98%
  • Packaging5g
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51494
  • Product description4-(Trifluoromethyl)nicotinic Acid
  • Packaging5g
  • Price$49
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberL19553
  • Product description4-(Trifluoromethyl)nicotinic acid, 98%
  • Packaging250mg
  • Price$68.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberL19553
  • Product description4-(Trifluoromethyl)nicotinic acid, 98%
  • Packaging1g
  • Price$126.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlichem
  • Product number158063662
  • Product description4-(Trifluoromethyl)nicotinic Acid
  • Packaging250mg
  • Price$700.4
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number158063662
  • Product description4-(Trifluoromethyl)nicotinic Acid
  • Packaging500mg
  • Price$1068.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number158063662
  • Product description4-(Trifluoromethyl)nicotinic Acid
  • Packaging1g
  • Price$1819.8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA114766
  • Product description4-(Trifluoromethyl)nicotinic Acid 98%
  • Packaging250mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA1476081
  • Product description4-(Trifluoromethyl)nicotinic Acid 98+%
  • Packaging250mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA1476081
  • Product description4-(Trifluoromethyl)nicotinic Acid 98+%
  • Packaging1g
  • Price$7
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA114766
  • Product description4-(Trifluoromethyl)nicotinic Acid 98%
  • Packaging1g
  • Price$7
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA114766
  • Product description4-(Trifluoromethyl)nicotinic Acid 98%
  • Packaging5g
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1476081
  • Product description4-(Trifluoromethyl)nicotinic Acid 98+%
  • Packaging5g
  • Price$30
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA114766
  • Product description4-(Trifluoromethyl)nicotinic Acid 98%
  • Packaging500g
  • Price$1175
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1476081
  • Product description4-(Trifluoromethyl)nicotinic Acid 98+%
  • Packaging500g
  • Price$1175
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA114766
  • Product description4-(Trifluoromethyl)nicotinic Acid 98%
  • Packaging10g
  • Price$42
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-40378 4-(Trifluoromethyl)nicotinic Acid 98% 5g $230 2021-12-16 Buy
AK Scientific J51494 4-(Trifluoromethyl)nicotinic Acid 5g $49 2021-12-16 Buy
Alfa Aesar L19553 4-(Trifluoromethyl)nicotinic acid, 98% 250mg $68.65 2024-03-01 Buy
Alfa Aesar L19553 4-(Trifluoromethyl)nicotinic acid, 98% 1g $126.65 2024-03-01 Buy
Alichem 158063662 4-(Trifluoromethyl)nicotinic Acid 250mg $700.4 2021-12-16 Buy
Alichem 158063662 4-(Trifluoromethyl)nicotinic Acid 500mg $1068.2 2021-12-16 Buy
Alichem 158063662 4-(Trifluoromethyl)nicotinic Acid 1g $1819.8 2021-12-16 Buy
Ambeed A114766 4-(Trifluoromethyl)nicotinic Acid 98% 250mg $5 2021-12-16 Buy
Ambeed A1476081 4-(Trifluoromethyl)nicotinic Acid 98+% 250mg $5 2021-12-16 Buy
Ambeed A1476081 4-(Trifluoromethyl)nicotinic Acid 98+% 1g $7 2021-12-16 Buy
Ambeed A114766 4-(Trifluoromethyl)nicotinic Acid 98% 1g $7 2021-12-16 Buy
Ambeed A114766 4-(Trifluoromethyl)nicotinic Acid 98% 5g $26 2021-12-16 Buy
Ambeed A1476081 4-(Trifluoromethyl)nicotinic Acid 98+% 5g $30 2021-12-16 Buy
Ambeed A114766 4-(Trifluoromethyl)nicotinic Acid 98% 500g $1175 2021-12-16 Buy
Ambeed A1476081 4-(Trifluoromethyl)nicotinic Acid 98+% 500g $1175 2021-12-16 Buy
Ambeed A114766 4-(Trifluoromethyl)nicotinic Acid 98% 10g $42 2021-12-16 Buy

Properties

Melting point :146-148 °C(lit.)
Boiling point :290.4±40.0 °C(Predicted)
Density :1.484±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO (Slightly), Methanol (Slightly)
pka :2.50±0.36(Predicted)
form :Solid
color :Pale Yellow to Dark Yellow
InChIKey :LMRJHNFECNKDKH-UHFFFAOYSA-N
CAS DataBase Reference :158063-66-2(CAS DataBase Reference)
EPA Substance Registry System :3-Pyridinecarboxylic acid, 4-(trifluoromethyl)- (158063-66-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

4-(Trifluoromethyl)-3-Pyridinecarboxylic Acid is a useful synthetic intermediate. It can be used to prepare pyridine carboxamides as palm site inhibitors of HCV NS5B polymerase. It can also be used to synthesize pyrazolylcarboxanilides as Ca2+ release-activated Ca2+ (CRAC) channel inhibitors.

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