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ChemicalBook >> CAS DataBase List >> N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide

N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide

N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide price.
  • $28 - $2200
  • Product name: N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide
  • CAS: 726169-73-9
  • MF: C23H20N6O
  • MW: 396.44
  • EINECS:
  • MDL Number:MFCD10565970
  • Synonyms:MGCD0103(Mocetinostat);MG0103;Mocetinostat (MGCD0103,MG0103);N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide;Mocetinostat (MGCD0103);N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide Mocetinostat (MGCD0103);Mocetinostat, >=98%;N-(2-Aminophenyl)-4-[[[4-(3-pyridyl)pyrimidin-2-yl]amino]methyl]benzamide
37 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Labseeker
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 1unit
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 10mM(in 1mL DMSO)
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 1000mg
  • ManufacturerAK Scientific
  • Product numberX7532
  • Product descriptionMocetinostat
  • Packaging5mg
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7532
  • Product descriptionMocetinostat
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7532
  • Product descriptionMocetinostat
  • Packaging50mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7532
  • Product descriptionMocetinostat
  • Packaging100mg
  • Price$191
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005251
  • Product descriptionMOCETINOSTAT 95.00%
  • Packaging5MG
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4089
  • Product descriptionMocetinostat(MGCD0103,MG0103)
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4089
  • Product descriptionMocetinostat(MGCD0103,MG0103)
  • Packaging5mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4089
  • Product descriptionMocetinostat(MGCD0103,MG0103)
  • Packaging10mM(in 1mL DMSO)
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4089
  • Product descriptionMocetinostat(MGCD0103,MG0103)
  • Packaging10mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4089
  • Product descriptionMocetinostat(MGCD0103,MG0103)
  • Packaging25mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60197
  • Product descriptionMocetinostat(MGCD0103) ≥98%
  • Packaging10mg
  • Price$168
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2505
  • Product descriptionMocetinostat-MGCD0103|MG0103 99%
  • Packaging25mg
  • Price$264
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546168
  • Product descriptionMocetinostat >98%
  • Packaging5mg
  • Price$190.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546168
  • Product descriptionMocetinostat >98%
  • Packaging25mg
  • Price$521.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181056
  • Product descriptionMGCD0103 (Mocetinostat) >98%
  • Packaging100mg
  • Price$606.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181056
  • Product descriptionMGCD0103 (Mocetinostat) >98%
  • Packaging250mg
  • Price$912.9
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X7532 Mocetinostat 5mg $38 2021-12-16 Buy
AK Scientific X7532 Mocetinostat 10mg $60 2021-12-16 Buy
AK Scientific X7532 Mocetinostat 50mg $119 2021-12-16 Buy
AK Scientific X7532 Mocetinostat 100mg $191 2021-12-16 Buy
American Custom Chemicals Corporation API0005251 MOCETINOSTAT 95.00% 5MG $330 2021-12-16 Buy
ApexBio Technology A4089 Mocetinostat(MGCD0103,MG0103) 1unit $28 2021-12-16 Buy
ApexBio Technology A4089 Mocetinostat(MGCD0103,MG0103) 5mg $84 2021-12-16 Buy
ApexBio Technology A4089 Mocetinostat(MGCD0103,MG0103) 10mM(in 1mL DMSO) $88 2021-12-16 Buy
ApexBio Technology A4089 Mocetinostat(MGCD0103,MG0103) 10mg $116 2021-12-16 Buy
ApexBio Technology A4089 Mocetinostat(MGCD0103,MG0103) 25mg $228 2021-12-16 Buy
Arctom CFN60197 Mocetinostat(MGCD0103) ≥98% 10mg $168 2021-12-16 Buy
Axon Medchem Axon2505 Mocetinostat-MGCD0103|MG0103 99% 25mg $264 2021-12-16 Buy
Biorbyt Ltd orb546168 Mocetinostat >98% 5mg $190.4 2021-12-16 Buy
Biorbyt Ltd orb546168 Mocetinostat >98% 25mg $521.9 2021-12-16 Buy
Biorbyt Ltd orb181056 MGCD0103 (Mocetinostat) >98% 100mg $606.9 2021-12-16 Buy
Biorbyt Ltd orb181056 MGCD0103 (Mocetinostat) >98% 250mg $912.9 2021-12-16 Buy

Properties

Melting point :>170oC (dec.)
Density :1.340±0.06 g/cm3(Predicted)
storage temp. :RT
solubility :Soluble in DMSO (up to 25 mg/ml)
pka :13.13±0.70(Predicted)
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Mocetinostat is an orally available inhibitor of histone deacetylases (HDACs) that selectively targets HDAC1 and 2 (IC50s = 0.15 and 0.29 μM, respectively), less potently inhibits HDAC3 and 11 (IC50s = 1.66 and 0.59 μM, respectively) and has negligible actions against HDAC4-8. It induces hyperacetylation of histones, causes cell cycle blockade, and induces apoptosis in cancer cells in vitro. Mocetinostat also has antitumor activity in vivo, blocking the growth of human tumor xenografts in mice. It also significantly reduces cardiac fibrosis following ischemic heart failure in mice.

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