N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine
![N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine price.](/CAS2/GIF/881202-45-5.gif)
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- $28 - $6480
- Product name: N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine
- CAS: 881202-45-5
- MF: C21H20N4
- MW: 328.41
- EINECS:200-256-5
- MDL Number:MFCD16620518
- Synonyms:N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine;JNJ 26854165;SerdeMetan;JNJ-26854165 (SerdeMetan);JNJ 26854165 N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine;N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine JNJ 26854165;JNJ-26854165, >=98%;N1-[2-(1H-indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-Benzene diamine
34 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 1mg
- 10mM(in 1mL DMSO)
- 1unit
- 5MG
- 2x5mg
- 10MG
- 25MG
- 50MG
- 100mg
- 250mg
- 1g
- 1000mg
- ManufacturerAK Scientific
- Product numberX7539
- Product descriptionSerdemetan
- Packaging1g
- Price$2273
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000886
- Product descriptionJNJ-26854165 95.00%
- Packaging5MG
- Price$462
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000886
- Product descriptionJNJ-26854165 95.00%
- Packaging10MG
- Price$494
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000886
- Product descriptionJNJ-26854165 95.00%
- Packaging25MG
- Price$580
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000886
- Product descriptionJNJ-26854165 95.00%
- Packaging50MG
- Price$727
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000886
- Product descriptionJNJ-26854165 95.00%
- Packaging1G
- Price$6480
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4204
- Product descriptionJNJ-26854165(Serdemetan)
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4204
- Product descriptionJNJ-26854165(Serdemetan)
- Packaging5mg
- Price$64
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4204
- Product descriptionJNJ-26854165(Serdemetan)
- Packaging10mM(in 1mL DMSO)
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4204
- Product descriptionJNJ-26854165(Serdemetan)
- Packaging25mg
- Price$224
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4204
- Product descriptionJNJ-26854165(Serdemetan)
- Packaging100mg
- Price$632
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1538
- Product descriptionJNJ26854165-Serdemetan 99%
- Packaging2x5mg
- Price$176
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181039
- Product descriptionJNJ-26854165 (Serdemetan) >98%
- Packaging100mg
- Price$690.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181039
- Product descriptionJNJ-26854165 (Serdemetan) >98%
- Packaging250mg
- Price$1356.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181039
- Product descriptionJNJ-26854165 (Serdemetan) >98%
- Packaging1000mg
- Price$2691.1
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFI151818
- Product descriptionJNJ 26854165
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X7539 | Serdemetan | 1g | $2273 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000886 | JNJ-26854165 95.00% | 5MG | $462 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000886 | JNJ-26854165 95.00% | 10MG | $494 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000886 | JNJ-26854165 95.00% | 25MG | $580 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000886 | JNJ-26854165 95.00% | 50MG | $727 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000886 | JNJ-26854165 95.00% | 1G | $6480 | 2021-12-16 | Buy |
| ApexBio Technology | A4204 | JNJ-26854165(Serdemetan) | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A4204 | JNJ-26854165(Serdemetan) | 5mg | $64 | 2021-12-16 | Buy |
| ApexBio Technology | A4204 | JNJ-26854165(Serdemetan) | 10mM(in 1mL DMSO) | $100 | 2021-12-16 | Buy |
| ApexBio Technology | A4204 | JNJ-26854165(Serdemetan) | 25mg | $224 | 2021-12-16 | Buy |
| ApexBio Technology | A4204 | JNJ-26854165(Serdemetan) | 100mg | $632 | 2021-12-16 | Buy |
| Axon Medchem | Axon1538 | JNJ26854165-Serdemetan 99% | 2x5mg | $176 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181039 | JNJ-26854165 (Serdemetan) >98% | 100mg | $690.2 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181039 | JNJ-26854165 (Serdemetan) >98% | 250mg | $1356.6 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181039 | JNJ-26854165 (Serdemetan) >98% | 1000mg | $2691.1 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FI151818 | JNJ 26854165 | 10mg | $95 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL in DMSO
form :solid
solubility :insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL in DMSO
form :solid
Safety Information
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Description
The E3 ubiquitin ligase known as murine double minute 2 (MDM2; HDM2 in humans) binds to and then ubiquitinates several proteins, most notably the tumor suppressor p53. JNJ-26854165 is an antagonist of MDM2 that suppresses the growth of cancer cell lines expressing wild-type p53 (IC50 values range from 240-440 nM). It induces p53-mediated transcription culminating in apoptotic death of acute leukemia cells. JNJ-26854165 is orally bioavailable and has anti-proliferative as well as apoptotic actions in various tumor models. As MDM2 interacts with and modulates several targets in addition to p53, JNJ-26854165 affects multiple signaling pathways.More related product prices
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![N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine](https://img.chemicalbook.com/ProductImageEN/2019-9/small/d330a174-c4e0-491b-b584-ffde058fc907.png){kind=small}
![N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine](/ProductImageEN/2021-04/small/7e13744f-fec7-45aa-a817-db4a379dc444.jpg){kind=small}
![N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine](/ProductImageEN/2021-10/small/c3b07bee-bcf1-40b4-b0ed-1f95d5a80c3e.jpg){kind=small}