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ChemicalBook >> CAS DataBase List >> CCG-100602

CCG-100602

CCG-100602 price.
  • $38 - $424
  • Product name: CCG-100602
  • CAS: 1207113-88-9
  • MF: C21H17ClF6N2O2
  • MW: 478.82
  • EINECS:
  • MDL Number:
  • Synonyms:CCG-100602;1-[3,5-bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)piperidine-3-carboxamide;3-Piperidinecarboxamide, 1-[3,5-bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)-;CCG-100602 >=98% (HPLC);CCG 100602,Inhibitor,transcription,inhibit,serum,myocardin,nuclear,SRF,CCG100602,MRTF-A,CCG-100602,Ras,localization
11 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number3485DG
  • Product description1-[3,5-Bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)piperidine-3-carboxamide
  • Packaging25mg
  • Price$282
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3485DG
  • Product description1-[3,5-Bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)piperidine-3-carboxamide
  • Packaging50mg
  • Price$424
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3687
  • Product descriptionCCG-100602
  • Packaging10mg
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3687
  • Product descriptionCCG-100602
  • Packaging25mg
  • Price$187
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3687
  • Product descriptionCCG-100602
  • Packaging50mg
  • Price$333
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10787
  • Product descriptionCCG-100602 ≥98%
  • Packaging5mg
  • Price$38
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10787
  • Product descriptionCCG-100602 ≥98%
  • Packaging10mg
  • Price$71
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10787
  • Product descriptionCCG-100602 ≥98%
  • Packaging25mg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10787
  • Product descriptionCCG-100602 ≥98%
  • Packaging50mg
  • Price$292
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML2292
  • Product descriptionCCG-100602 ≥98% (HPLC)
  • Packaging5mg
  • Price$63.1
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML2292
  • Product descriptionCCG-100602 ≥98% (HPLC)
  • Packaging25mg
  • Price$179
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3485DG 1-[3,5-Bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)piperidine-3-carboxamide 25mg $282 2021-12-16 Buy
AK Scientific 3485DG 1-[3,5-Bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)piperidine-3-carboxamide 50mg $424 2021-12-16 Buy
ApexBio Technology C3687 CCG-100602 10mg $79 2021-12-16 Buy
ApexBio Technology C3687 CCG-100602 25mg $187 2021-12-16 Buy
ApexBio Technology C3687 CCG-100602 50mg $333 2021-12-16 Buy
Cayman Chemical 10787 CCG-100602 ≥98% 5mg $38 2024-03-01 Buy
Cayman Chemical 10787 CCG-100602 ≥98% 10mg $71 2024-03-01 Buy
Cayman Chemical 10787 CCG-100602 ≥98% 25mg $166 2024-03-01 Buy
Cayman Chemical 10787 CCG-100602 ≥98% 50mg $292 2024-03-01 Buy
Sigma-Aldrich SML2292 CCG-100602 ≥98% (HPLC) 5mg $63.1 2024-03-01 Buy
Sigma-Aldrich SML2292 CCG-100602 ≥98% (HPLC) 25mg $179 2024-03-01 Buy

Properties

storage temp. :-20°C
solubility :≤0.2mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
form :powder
color :white to beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

The Rho family of small GTPases play an important role in transduction of cell signaling events associated with several human cancers. CCG-1423 is a specific inhibitor of Rho pathway-mediated signaling and activation of serum response factor (SRF) transcription. The site of inhibition in the pathway is not precisely defined but CCG-1423 appears to act on some aspect of the interaction of SRF with its transcriptional cofactor megakaryoblastic leukemia 1 (MKL1) at a point upstream of DNA binding. CCG-100602 is a CCG-1423 analog developed for improved selectivity, potency, and attenuated cytotoxicity relative to its parent compound. CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells with an IC50 value of 9.8 μM. At 100 μM, CCG-100602 demonstrates 72% inhibition of PC-3 cell invasion into a Matrigel model of metastasis, exhibiting an efficacy:toxicity profile superior to that of CCG-1423 at 10 μM.