JNJ 31020028
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- $68 - $1900
- Product name: JNJ 31020028
- CAS: 1094873-14-9
- MF: C34H36FN5O2
- MW: 565.68
- EINECS:
- MDL Number:MFCD18782744
- Synonyms:JNJ 31020028;N-(4-(4-(2-(diethylamino)-2-oxo-1-phenylethyl)piperazin-1-yl)-3-fluorophenyl)-2-(pyridin-3-yl)benzamide;N,N-Diethyl-4-[2-fluoro-4-[[2-(3-pyridinyl)benzoyl]amino]phenyl]-alpha-phenyl-1-piperazineacetamide;4-[1-(BENZENESULFONYL)-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRROLO[2,3-B]PYRIDIN-2-YL]BENZALDEHYDE;JNJ31020028, >98%;JNJ-31020028?, >98%;CS-1745;JNJ-31020028;JNJ 31020028
25 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Usbiological
Package
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2882DC
- Product descriptionJnj-31020028
- Packaging1mg
- Price$174
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2882DC
- Product descriptionJnj-31020028
- Packaging10mg
- Price$397
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0013956
- Product descriptionJNJ-31020028 95.00%
- Packaging5MG
- Price$660
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4827
- Product descriptionJNJ-31020028
- Packaging5mg
- Price$221
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4827
- Product descriptionJNJ-31020028
- Packaging10mg
- Price$378
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4827
- Product descriptionJNJ-31020028
- Packaging50mg
- Price$1166
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4827
- Product descriptionJNJ-31020028
- Packaging100mg
- Price$1890
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFJ137688
- Product descriptionJNJ 31020028
- Packaging10mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFJ137688
- Product descriptionJNJ 31020028
- Packaging50mg
- Price$612.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18407
- Product descriptionJNJ-31020028 ≥95%
- Packaging1mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18407
- Product descriptionJNJ-31020028 ≥95%
- Packaging5mg
- Price$152
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18407
- Product descriptionJNJ-31020028 ≥95%
- Packaging10mg
- Price$268
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18407
- Product descriptionJNJ-31020028 ≥95%
- Packaging25mg
- Price$586
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM169974
- Product descriptionN-(4-(4-(2-(diethylamino)-2-oxo-1-phenylethyl)piperazin-1-yl)-3-fluorophenyl)-2-(pyridin-3-yl)benzamide 98%
- Packaging100mg
- Price$355
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3499
- Product descriptionJNJ-31020028 98.62%
- Packaging5mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3499
- Product descriptionJNJ-31020028 98.62%
- Packaging10mg
- Price$180
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2882DC | Jnj-31020028 | 1mg | $174 | 2021-12-16 | Buy |
| AK Scientific | 2882DC | Jnj-31020028 | 10mg | $397 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0013956 | JNJ-31020028 95.00% | 5MG | $660 | 2021-12-16 | Buy |
| ApexBio Technology | B4827 | JNJ-31020028 | 5mg | $221 | 2021-12-16 | Buy |
| ApexBio Technology | B4827 | JNJ-31020028 | 10mg | $378 | 2021-12-16 | Buy |
| ApexBio Technology | B4827 | JNJ-31020028 | 50mg | $1166 | 2021-12-16 | Buy |
| ApexBio Technology | B4827 | JNJ-31020028 | 100mg | $1890 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FJ137688 | JNJ 31020028 | 10mg | $175 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FJ137688 | JNJ 31020028 | 50mg | $612.5 | 2021-12-16 | Buy |
| Cayman Chemical | 18407 | JNJ-31020028 ≥95% | 1mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 18407 | JNJ-31020028 ≥95% | 5mg | $152 | 2024-03-01 | Buy |
| Cayman Chemical | 18407 | JNJ-31020028 ≥95% | 10mg | $268 | 2024-03-01 | Buy |
| Cayman Chemical | 18407 | JNJ-31020028 ≥95% | 25mg | $586 | 2024-03-01 | Buy |
| Chemenu | CM169974 | N-(4-(4-(2-(diethylamino)-2-oxo-1-phenylethyl)piperazin-1-yl)-3-fluorophenyl)-2-(pyridin-3-yl)benzamide 98% | 100mg | $355 | 2021-12-16 | Buy |
| ChemScene | CS-3499 | JNJ-31020028 98.62% | 5mg | $110 | 2021-12-16 | Buy |
| ChemScene | CS-3499 | JNJ-31020028 98.62% | 10mg | $180 | 2021-12-16 | Buy |
Properties
Boiling point :677.5±55.0 °C(Predicted)
Density :1.228±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 21.5 mg/mL (38.01 mM; Need ultrasonic and warming)
form :Powder
pka :12.14±0.70(Predicted)
Density :1.228±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 21.5 mg/mL (38.01 mM; Need ultrasonic and warming)
form :Powder
pka :12.14±0.70(Predicted)
Safety Information
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| Signal word: | Warning | |||||||
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Description
JNJ-31020028 is a brain-permeable selective antagonist of the neuropeptide Y (NPY) receptor Y2 (IC50s = 8.51, 6.03, and 6.17 nM for human, rat, and mouse receptors, respectively) with over 100-fold selectivity for Y2 over Y1, Y4, and Y5 receptors. JNJ-31020028 inhibits calcium release induced by peptide YY in a functional assay in KAN-TS cells (pKB = 8.04) and blocks NPY(13-36)-induced decreases in twitch contraction amplitude in isolated rat vas deferens (IC50 = 7.94 nM). Administration of JNJ-31020028 to rats during abstinence (20 mg/kg per day, i.p.) reverses nicotine-induced social anxiety-like behavior and increases hippocampal Y2 receptor mRNA levels. It reverses withdrawal-induced anxiety-like behavior in rats in the elevated plus maze following a single bolus dose of alcohol when administered at a dose of 15 mg/kg. In an olfactory bulbectomized rat model of depression, chronic JNJ-31020028 treatment (10 nmol per day, i.c.v.) decreases immobility time in the forced swim test but has no effect in control animals.More related product prices
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