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ChemicalBook >> CAS DataBase List >> PCI 34051

PCI 34051

PCI 34051 price.
  • $70 - $2395.3
  • Product name: PCI 34051
  • CAS: 950762-95-5
  • MF: C17H16N2O3
  • MW: 296.32
  • EINECS:
  • MDL Number:MFCD11114393
  • Synonyms:N-hydroxy-1-(4-Methoxybenzyl)-1H-indole-6-carboxaMide;PCI 34051;PCI-34051;1-(4-methoxybenzyl)-N-hydroxy-1H-indole-6-carboxamide;1H-Indole-6-carboxamide, N-hydroxy-1-[(4-methoxyphenyl)methyl]-;N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide;PCI-34051;PCI 34051;N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide
27 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • BroadPharm
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 10mg
  • 50mg
  • 50
  • 100mg
  • 250mg
  • 10
  • 1g
  • ManufacturerAK Scientific
  • Product number2632AH
  • Product description1-(4-Methoxybenzyl)-N-hydroxy-1H-indole-6-carboxamide
  • Packaging100mg
  • Price$865
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4091
  • Product descriptionPCI-34051
  • Packaging100mg
  • Price$710
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60402
  • Product descriptionPCI-34051
  • Packaging10mg
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1853
  • Product descriptionPCI34051 98%
  • Packaging10mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146092
  • Product descriptionPCI-34051 >98%
  • Packaging100mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146092
  • Product descriptionPCI-34051 >98%
  • Packaging250mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146092
  • Product descriptionPCI-34051 >98%
  • Packaging1g
  • Price$2395.3
  • Updated2021-12-16
  • Buy
  • ManufacturerBroadPharm
  • Product numberBP-25403
  • Product descriptionPCI34051
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10444
  • Product descriptionPCI 34051 ≥95%
  • Packaging5mg
  • Price$77
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10444
  • Product descriptionPCI 34051 ≥95%
  • Packaging10mg
  • Price$144
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10444
  • Product descriptionPCI 34051 ≥95%
  • Packaging50mg
  • Price$602
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10444
  • Product descriptionPCI 34051 ≥95%
  • Packaging100mg
  • Price$829
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM148884
  • Product descriptionN-Hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide 95%+
  • Packaging100mg
  • Price$668
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1277
  • Product descriptionPCI-34051 99.38%
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1277
  • Product descriptionPCI-34051 99.38%
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1277
  • Product descriptionPCI-34051 99.38%
  • Packaging50mg
  • Price$510
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2632AH 1-(4-Methoxybenzyl)-N-hydroxy-1H-indole-6-carboxamide 100mg $865 2021-12-16 Buy
ApexBio Technology A4091 PCI-34051 100mg $710 2021-12-16 Buy
Arctom CFN60402 PCI-34051 10mg $238 2021-12-16 Buy
Axon Medchem Axon1853 PCI34051 98% 10mg $99 2021-12-16 Buy
Biorbyt Ltd orb146092 PCI-34051 >98% 100mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb146092 PCI-34051 >98% 250mg $1208.7 2021-12-16 Buy
Biorbyt Ltd orb146092 PCI-34051 >98% 1g $2395.3 2021-12-16 Buy
BroadPharm BP-25403 PCI34051 10mg $150 2021-12-16 Buy
Cayman Chemical 10444 PCI 34051 ≥95% 5mg $77 2024-03-01 Buy
Cayman Chemical 10444 PCI 34051 ≥95% 10mg $144 2024-03-01 Buy
Cayman Chemical 10444 PCI 34051 ≥95% 50mg $602 2024-03-01 Buy
Cayman Chemical 10444 PCI 34051 ≥95% 100mg $829 2024-03-01 Buy
Chemenu CM148884 N-Hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide 95%+ 100mg $668 2021-12-16 Buy
ChemScene CS-1277 PCI-34051 99.38% 5mg $70 2021-12-16 Buy
ChemScene CS-1277 PCI-34051 99.38% 10mg $120 2021-12-16 Buy
ChemScene CS-1277 PCI-34051 99.38% 50mg $510 2021-12-16 Buy

Properties

Density :1.25
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥14.8 mg/mL in DMSO
form :Powder
pka :9.16±0.30(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

PCI 34051 is a potent histone deacetylase (HDAC) 8 inhibitor (IC50 = 0.01 μM) with >200-fold selectivity over HDAC isoforms 1, 2, 3, 6, and 10 (IC50s = 4, >50, >50, 2.9, and 13 μM, respectively). PCI 34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias (GI50s = 2.4 - 4 μM), but not in other hematopoietic or solid tumor lines. This compound has also been used to support a critical role for HDAC8 in the coordinated deacetylation of the core cohesion component SMC3 during mitosis.

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