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ChemicalBook >> CAS DataBase List >> Suramin sodium

Suramin sodium

Suramin sodium price.
  • $28 - $1389
  • Product name: Suramin sodium
  • CAS: 129-46-4
  • MF: C51H34N6Na6O23S6
  • MW: 1429.17
  • EINECS:204-949-3
  • MDL Number:MFCD00210217
  • Synonyms:sodiumsuramin ;SURAMIN SODIUM, 98+%;8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfoni;8-[[4-Methyl-3-[[3-[[3-[[2-methyl-5-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonic acid;F-309;Naganol;Suramin hexasodium salt,98%;Suppressor
26 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AHH
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10mM(in 1mL H2O)
  • 1mg
  • 5MG
  • 25MG
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3575-M050
  • Product descriptionSuramin hexasodium salt ≥98%(PharmaceuticalGrade).
  • Packaging50mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-58880
  • Product descriptionSuraminsodium 98%
  • Packaging1g
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61707
  • Product descriptionSuramin hexasodium salt 98+%
  • Packaging250mg
  • Price$570
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61707
  • Product descriptionSuramin hexasodium salt 98+%
  • Packaging500mg
  • Price$834
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61707
  • Product descriptionSuramin hexasodium salt 98+%
  • Packaging1g
  • Price$1389
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA397022
  • Product descriptionSodium8,8'-((3,3'-((3,3'-(carbonylbis(azanediyl))bis(benzoyl))bis(azanediyl))bis(4-methylbenzoyl))bis(azanediyl))bis(naphthalene-1,3,5-trisulfonate) 98+%
  • Packaging100mg
  • Price$246
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA397022
  • Product descriptionSodium8,8'-((3,3'-((3,3'-(carbonylbis(azanediyl))bis(benzoyl))bis(azanediyl))bis(4-methylbenzoyl))bis(azanediyl))bis(naphthalene-1,3,5-trisulfonate) 98+%
  • Packaging250mg
  • Price$358
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA397022
  • Product descriptionSodium8,8'-((3,3'-((3,3'-(carbonylbis(azanediyl))bis(benzoyl))bis(azanediyl))bis(4-methylbenzoyl))bis(azanediyl))bis(naphthalene-1,3,5-trisulfonate) 98+%
  • Packaging1g
  • Price$925
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0009865
  • Product descriptionSURAMIN HEXASODIUM 95.00%
  • Packaging5MG
  • Price$459.99
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6752
  • Product descriptionSuramin hexasodium salt
  • Packaging10mM(in 1mL H2O)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6752
  • Product descriptionSuramin hexasodium salt
  • Packaging50mg
  • Price$93
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11126
  • Product descriptionSuramin (sodium salt) ≥98%
  • Packaging100mg
  • Price$105
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11126
  • Product descriptionSuramin (sodium salt)
  • Packaging250mg
  • Price$249
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4445
  • Product descriptionSuramin, Sodium Salt 99.93%
  • Packaging50mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003985
  • Product descriptionSuramin, Sodium Salt 98+%
  • Packaging50mg
  • Price$193
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003985
  • Product descriptionSuramin, Sodium Salt 98+%
  • Packaging100mg
  • Price$300
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3575-M050 Suramin hexasodium salt ≥98%(PharmaceuticalGrade). 50mg $60 2021-12-16 Buy
AHH MT-58880 Suraminsodium 98% 1g $230 2021-12-16 Buy
Alfa Aesar J61707 Suramin hexasodium salt 98+% 250mg $570 2023-06-20 Buy
Alfa Aesar J61707 Suramin hexasodium salt 98+% 500mg $834 2021-12-16 Buy
Alfa Aesar J61707 Suramin hexasodium salt 98+% 1g $1389 2021-12-16 Buy
Ambeed A397022 Sodium8,8'-((3,3'-((3,3'-(carbonylbis(azanediyl))bis(benzoyl))bis(azanediyl))bis(4-methylbenzoyl))bis(azanediyl))bis(naphthalene-1,3,5-trisulfonate) 98+% 100mg $246 2021-12-16 Buy
Ambeed A397022 Sodium8,8'-((3,3'-((3,3'-(carbonylbis(azanediyl))bis(benzoyl))bis(azanediyl))bis(4-methylbenzoyl))bis(azanediyl))bis(naphthalene-1,3,5-trisulfonate) 98+% 250mg $358 2021-12-16 Buy
Ambeed A397022 Sodium8,8'-((3,3'-((3,3'-(carbonylbis(azanediyl))bis(benzoyl))bis(azanediyl))bis(4-methylbenzoyl))bis(azanediyl))bis(naphthalene-1,3,5-trisulfonate) 98+% 1g $925 2021-12-16 Buy
American Custom Chemicals Corporation INB0009865 SURAMIN HEXASODIUM 95.00% 5MG $459.99 2021-12-16 Buy
ApexBio Technology B6752 Suramin hexasodium salt 10mM(in 1mL H2O) $60 2021-12-16 Buy
ApexBio Technology B6752 Suramin hexasodium salt 50mg $93 2021-12-16 Buy
Cayman Chemical 11126 Suramin (sodium salt) ≥98% 100mg $105 2024-03-01 Buy
Cayman Chemical 11126 Suramin (sodium salt) 250mg $249 2024-03-01 Buy
ChemScene CS-4445 Suramin, Sodium Salt 99.93% 50mg $300 2021-12-16 Buy
Crysdot CD31003985 Suramin, Sodium Salt 98+% 50mg $193 2021-12-16 Buy
Crysdot CD31003985 Suramin, Sodium Salt 98+% 100mg $300 2021-12-16 Buy

Properties

Melting point :>260°C (dec.)
storage temp. :0-6°C
solubility :H2O: >10mg/mL
form :Crystalline Powder
color :White
PH :pH(10g/l, 25℃) : 5.0~8.0
Water Solubility :soluble
BRN :3694087
Stability :Hygroscopic
InChIKey :VAPNKLKDKUDFHK-UHFFFAOYSA-H

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P321 Specific treatment (see … on this label).
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

Suramin is a polysulfonated naphthylurea that inhibits the binding of calmodulin to recognition sites on the ryanodine receptor-1 (IC50 = 4.9 μM), blocks G protein coupling to GPCRs, and non-selectively antagonizes P2 purinergic receptors (10-100 μM). Suramin also acts as a non-specific competitor of glycosaminoglycan binding to a variety of targets including TGFβ, PDGF, and FGF and additionally inhibits insulin-like growth factor-l, EGF, PKC activity, TNF, IL-2, transferrin, and Apo-B. While originally used as an early stage treatment of trypanosome-caused onchocerciasis (African river blindness) and African trypanosomiasis (African sleeping sickness), suramin has been under clinical evaluation for its potential to regress a number of cancer cell lines, including non-small cell lung cancer, advanced breast cancer, hormone refractory prostate cancer, metastatic renal cell cancer, colorectal cancer, and high-grade gliomas.

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