88979-61-7 Basic information More..
Product Name:BAFILOMYCIN C1
Synonyms:2-Demethyl-2-methoxy-24-methylhygrolidin;Antibiotic L-681110A1;L-681110A1;BAFILOMYCIN C1;Bafilomycin C1, from Streptomyces griseus;2-Butenedioic acid (2E)-, 1-[(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-yl] ester;Bafilomycin C-1,Bafilomycin C1
CAS:88979-61-7
MF:C39H60O12
MW:720.89
EINECS:
Mol File:88979-61-7.mol
88979-61-7

Use

Bafilomycin C1 is a member of a potent family of macrocyclic lactones. Bafilomycin C1 shares a similar mode of action and activity as its more accessible A1 analogue. Bafilomycin C1 is broadly active against bacteria, fungi, insects, nematodes and cestodes. Bafilomycin C1 has attracted interest as a potential agent for treating osteoporosis. The presence of the fumarate group provides an ideal ligand for affinity chromatography of V-ATPase.

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