| | 75541-83-2 Basic information More.. |
| Product Name: | EXO1 | | Synonyms: | 4-FLUORO-BZ-2-ABZ-OME;2-(4-FLUOROBENZOYLAMINO)BENZOIC ACID METHYL ESTER;2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE;2-(4-Fluoro-benzoylami;2-(4-Fluorobenzoylamino)benzoic acid methyl ester, 2-(4-Fluorobenzoylamino)methylbenzoate;EOX 1;EXOCYTIC INHIBITOR 1;EXO1 | | CAS: | 75541-83-2 | | MF: | C15H12FNO3 | | MW: | 273.26 | | EINECS: | | | Mol File: | 75541-83-2.mol |  |
Use
Exo1 is a cell-permeable, reversible inhibitor of exocytosis (IC50 = 20 μM). It interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum by dissociating the GTPase activator ADP-ribosylation factor (ARF1) from Golgi membranes, which leads to a consequent collapse of the Golgi apparatus.
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75541-83-2
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