| | 70763-62-1 Basic information More.. |
| Product Name: | 2-Deoxy-2-fluoro-L-fucose | | Synonyms: | 2-Deoxy-2-fluoro-L-fucose;(3S,4R,5S,6S)-3-Fluoro-6-methyl-tetrahydropyran-2,4,5-triol;2-Deoxy-2-fluoro-L-fucose, Min. 98%;L-Galactose, 2,6-dideoxy-2-fluoro-;2,6-dideoxy-2-fluoro-L-Galactose;(2S,3R,4R,5S)-2-Fluoro-3,4,5-trihydroxyhexanal;2-Deoxy-2-fluoro-L-fucose, CAS NO: 70763-62-1;2-fluorofucose | | CAS: | 70763-62-1 | | MF: | C6H11FO4 | | MW: | 166.15 | | EINECS: | | | Mol File: | 70763-62-1.mol |  |
Use
Fucose is a deoxyhexose that is present in many organisms. Fucose-containing glycans, generated by fucosyltransferase using GDP-fucose, have roles in cell signaling, cell-cell interactions, and blood properties. 2-deoxy-2-fluoro L-Fucose is a fluorinated fucose analog. It can be metabolized inside the cell to a substrate-based inhibitor of fucosyltransferases. Alternatively, it can be converted in vitro to GDP-2-deoxy-2-fluoro L-fucose, a competitive inhibitor of α1,3-fucosyltransferase V (Ki = 4.2 μM).
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70763-62-1
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