| | 73573-88-3 Basic information More.. |
| Product Name: | Mevastatin | | Synonyms: | Butanoic acid, 2-methyl-, (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-;,8-beta(2s*,4s*),8a-beta))-;antibioticml236b;butanoicacid,2-methyl-,1,2,3,7,8,8a-hexahydro-7-methyl-8-(2-(tetrahydro-4-hy;compactin(penicillium);(S)-2-Methylbutyric acid [(1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]naphthalen-1-yl] ester;2-Methyl-butanoic acid [1S-[1-α(R*),7-β,8-β(2S*,4S*),8a-β]]-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester;Mevastatin, >=97% | | CAS: | 73573-88-3 | | MF: | C23H34O5 | | MW: | 390.51 | | EINECS: | 700-442-0 | | Mol File: | 73573-88-3.mol |  |
Use
Mevastatin (compactin) is a diterpene produced by several species of the genera Penicillium and Monascus, first reported in 1976. Mevastatin, the prototype of the statin class, is a potent competitive inhibitor of HMG-CoA reductase, a regulatory enzyme for cholesterol biosynthesis. Mevastatin has also been shown to induce apoptosis by inhibiting post-translational prenylation of proteins such as Ras, increasing eNOS mRNA and protein levels by blocking the geranylgeranylation of Rho, and inhibiting myoblast fusion. It induces cell cycle arrest in late G1 phase and may induce bone morphogenic protein-2 (BMP-2).
- Mevastatin
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- US $0.00-0.00 / g
- 2023-11-01
- CAS:73573-88-3
- Min. Order: 1g
- Purity: >=98.5%
- Supply Ability: 500kg
- Mevastatin
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- US $0.00 / KG
- 2023-09-06
- CAS:73573-88-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
- Mevastatin
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- US $15.00-10.00 / KG
- 2021-07-13
- CAS:73573-88-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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73573-88-3
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