| | 112885-41-3 Basic information More.. |
| Product Name: | Mosapride | | Synonyms: | 4-AMINO-5-CHLORO-2-ETHOXY-N-[[[4-(4-FLUOROPHENYL)METHYL]-2-MORPHOLINYL]METHYL]-BENZAMIDE;((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide/mosapride;4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)-2-Morpholinyl)Methyl)Benzamide/Mosapride;MOSAPRIDE;Mosapride/4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)-2-Morpholinyl)Methyl)Benzamide;Mosapid;Mosid-MT;Moza | | CAS: | 112885-41-3 | | MF: | C21H25ClFN3O3 | | MW: | 421.89 | | EINECS: | | | Mol File: | 112885-41-3.mol |  |
Use
Mosapride citrate, a new gastroprokinetic benzamide was introduced in
Japan as Gasmotin for the relief of gastrointestinal symptoms in patients with
chronic gastritis, gastro-oesophageal reflux, dyspepsia and post-surgery use.
Mosapride is synthesized by final amidation between the corresponding benzoic
acid, itself obtained in 3 steps from methyl 4-acetamido salicylate, and the
appropriate 2-aminomethyl-morpholine. Mosapride is a 5-HT4 partial agonist
without notable activity for D2, 5-HT1 , 5-HT2, alpha-1 and alpha-2 receptors. In
dogs, mosapride was as potent as cisapride to stimulate antral and duodenal
motility. In most of species including man, mosapride undergoes extensive
cleavage to a N-debenzylated metabolite which retains partial 5-HT4 activity but
has potent 5-HT3 antagonist activity.
- Mosapride
-
- US $15.00-10.00 / KG
- 2021-07-13
- CAS:112885-41-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Mosapride
-
- US $15.00-10.00 / KG
- 2021-07-09
- CAS:112885-41-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Mosapride
-
- US $15.00-10.00 / KG
- 2021-07-02
- CAS:112885-41-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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112885-41-3
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