565460-15-3 Basic information More..
Product Name:URB602
Synonyms:URB602;Biphenyl-3-yl Carbamic Acid, Cyclohexyl Ester;cyclohexyl biphenyl-3-ylcarbaMate;[1,1’-Biphenyl]-3-yl-carbamic acid cyclohexyl ester;Monoacylglycerol Lipase Inhibitor, URB602;N-[1,1'-Biphenyl]-3-yl-;Cyclohexyl [1,1'-biphenyl]-3-ylcarbaMate;Carbamic acid, N-[1,1'-biphenyl]-3-yl-, cyclohexyl ester
CAS:565460-15-3
MF:C19H21NO2
MW:295.38
EINECS:
Mol File:565460-15-3.mol
565460-15-3

Use

URB602 is a selective inhibitor of MGL, exhibiting an IC50 of 28 μM for the rat brain enzyme. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 μM, or other lipid metabolizing enzymes such as diacylglycerol lipase or cyclooxygenase-2.5 6 Inhibition of 2-AG hydrolysis is associated with enhanced stress-induced analgesia and may represent a novel drug target in pain and stress management.

URB602 manufacturers

  • URB602
  • US $9.80 / KG
  • 2020-01-13
  • CAS:565460-15-3
  • Min. Order: 1g
  • Purity: ≥99%
  • Supply Ability: 100kg
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