57333-96-7 Basic information More..
Product Name:Tacalcitol
Synonyms:(1α,3β-5Z,7E,24R)-9,10-Secoholesta-5,7,10(19)-triene-1,3,24-triol;lα,24-Dihydroxycholecalciferol;lα,24R-Dihy-droxyvitamin D3;[5Z,7E,24R,(+)]-9,10-Secocholesta-5,7,10(19)-triene-1α,3β,24-triol;1α,24(R)-Dihydroxyvitamin D3;1α,24R-Dihydroxyvitamin D3;(1a,3b,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol;C12919
CAS:57333-96-7
MF:C27H44O3
MW:416.64
EINECS:
Mol File:57333-96-7.mol
57333-96-7

Use

Tacalcitol, the second vitamin D analog developed as a topical antipsoriatic, was introduced for keratosis, psoriasis, ichthyosis, pityriasis rubra pilaris and palmoplantar pustulosis and keratoderma. It shows improvement in appearance of skin lesions for psoriasis patients without significant side effects. In patients with psoriasis vulgaris, it effectively inhibits keratinocyte growth. Some in vitro studies have shown that tacalcitol inhibits interleukin-1-α-induced granulocyte macrophage colony-stimulating-factor mRNA expression of the human dermal microvascular endothelial cells, which may be involved in mediation of angioproliferation in skin inflammation.

Tacalcitol manufacturers

  • Tacalcitol
  • US $0.00 / kg
  • 2023-03-13
  • CAS:57333-96-7
  • Min. Order: 1kg
  • Purity: 99.0%min. HPLC
  • Supply Ability: 1000kg
  • Tacalcitol
  • US $15.00-10.00 / KG
  • 2021-07-13
  • CAS:57333-96-7
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
  • Tacalcitol
  • US $15.00-10.00 / KG
  • 2021-07-09
  • CAS:57333-96-7
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
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