23288-49-5 Basic information More..
Product Name:Probucol
Synonyms:PROBUCOL;4,4’-((1-methylethylidene)bis(thio))bis(2,6-bis(1,1-dimethylethyl)-pheno;biphenabid;bisbid;bisphenabid;Probucol (200 mg);Probucol-[13C3];Bis(3,5-di-tert-butyl-4-hydroxyphenyl) Mercaptole Acetone
CAS:23288-49-5
MF:C31H48O2S2
MW:516.84
EINECS:245-560-9
Mol File:23288-49-5.mol
23288-49-5

Use

Probucol, 4,4' -[(1-methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)phenol], DH-581(Lorelco), is a chemical agent that was developed for the plasticsand rubber industry in the 1960s. The probucol moleculehas two tertiary butylphenol groups linked by a dithiopropylidenebridge, giving it a high lipophilic character with strongantioxidant properties. In humans, it causes reduction of bothliver and serum cholesterol levels, but it does not alter plasmatriglycerides. It reduces LDL and (to a lesser extent) HDLlevels by a unique mechanism that is still not clearly delineated.The reduction of HDL may be caused by the ability ofprobucol to inhibit the synthesis of apoprotein A-1, a majorprotein component of HDL. It is effective at reducing levelsof LDL and is used in hyperlipoproteinemias characterized byelevated LDL levels.

Probucol manufacturers

  • Probucol
  • US $30.00 / KG
  • 2021-10-20
  • CAS:23288-49-5
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 9000kg/per week
  • Probucol USP/EP/BP
  • US $1.10 / g
  • 2021-08-06
  • CAS:23288-49-5
  • Min. Order: 1g
  • Purity: 99.9%
  • Supply Ability: 100 Tons min
  • Probucol
  • US $15.00-10.00 / KG
  • 2021-07-13
  • CAS:23288-49-5
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
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