114-86-3 Basic information More..
Product Name:Phenformin
Synonyms:(phenylethyl)biguanide;1-phenethyl-biguanid;azucaps;beta-PEBG;beta-Phenethybiguanide;beta-Phenethylbiguanide;Biguanide, 1-phenethyl-;cronoformin
CAS:114-86-3
MF:C10H15N5
MW:205.26
EINECS:204-057-4
Mol File:114-86-3.mol
114-86-3

Use

Phenformin, a biguanide with oral hypoglycaemic activity, was introduced in 1957 for the management of diabetes mellitus. By 1970 its use had been associated with incidences of lactic acidosis and by 1976 clinical studies had conclusively demonstrated that the hazards of phenformin treatment outweighed the benefits. Preparations containing phenformin were withdrawn in several countries and their use restricted in others. Elsewhere, however, proprietary preparations containing this drug may remain available. The related biguanide, buformin, has been also associated with lactic acidosis and has been subjected to similar restrictions as phenformin, whereas there is some evidence that metformin is less liable to induce lactic acidosis. (Reference: (WHODI) WHO Drug Information, 2, 4, 1977)

Phenformin manufacturers

  • Phenformin
  • US $10.50 / KG
  • 2023-03-06
  • CAS:114-86-3
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 ton
  • Phenformin
  • US $1.10 / g
  • 2022-05-13
  • CAS:114-86-3
  • Min. Order: 1g
  • Purity: 99.0% Min
  • Supply Ability: 100 Tons
  • phenformin
  • US $0.00 / gram
  • 2022-02-18
  • CAS:114-86-3
  • Min. Order: 1gram
  • Purity: 99%
  • Supply Ability: 10kg
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