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| Product Name: | Dimethyl fumarate | | Synonyms: | But-2-enedioicaciddimethylester;Fumaric acid, bis-methyl ester;Dimethyl furmarate;DiMethyl fuMarate, 99% 100GR;DiMethyl fuMarate, 99% 25GR;trans-butenedioicacid,dimethylester;trans-butenedioicaciddimethylester;Dimethyl fumarate,99% | | CAS: | 624-49-7 | | MF: | C6H8O4 | | MW: | 144.13 | | EINECS: | 210-849-0 | | Mol File: | 624-49-7.mol |  |
Use
Dimethyl fumarate is the methyl ester of fumaric acid. Dimethyl fumarate, marketed in Germany under the trade name of Fumaderm, is used for oral therapy of psoriasis in combination with other drugs. Later it has been used to treat adults with relapsing multiple sclerosis[a chronic inflammatory, demyelinating and neurodegenerative disease of the CNS resulting in neurological disability] since 2013(trade name Tecfidera). Dimethyl fumarate is thought to have immunomodulatory properties without significant immunosuppression. In preclinical studies, dimethyl fumarate exhibited anti-inflammatory and cytoprotective properties that are generally thought to be mediated via activation of the nuclear factor [erythroid-derived 2]-like 2 transcriptional pathway, which is involved in the cellular response to oxidative stress.
- Dimethyl fumarate
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- US $6.00 / kg
- 2024-05-30
- CAS:624-49-7
- Min. Order: 1kg
- Purity: More than 99%
- Supply Ability: 2000KG/Month
- Dimethyl fumarate
-
- US $6.00 / KG
- 2024-04-12
- CAS:624-49-7
- Min. Order: 1KG
- Purity: More than 99%
- Supply Ability: 500KG/Month
- Dimethyl fumarate
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- US $99.00 / KG
- 2024-01-23
- CAS:624-49-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20 tons
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624-49-7
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