146374-27-8 Basic information More..
Product Name:tert-Butanesulfinamide
Synonyms:TERT-BUTYLSULPHINAMIDE;2-METHYL-2-PROPANESULFINAMIDE, RACEMIC,&;Racemic 2-Methyl-2-propanesulfinamide;TERT-BUTANESULFINAMIDE;(S)-(-)-2-METHYL-2-PROPANESULFINAMIDE, 98+%;REF DUPL: (S)-(+)-t-Butylsulfinamide;Racemic tert Butylsulfinamide;Ter butyl sulfinicaMide
CAS:146374-27-8
MF:C4H11NOS
MW:121.2
EINECS:1312995-182-4
Mol File:146374-27-8.mol
146374-27-8

Use

(S)-tert-Butanesulfinamide (also known as 2-Methyl-2-propanesulfinamide) is used for the synthesis of 4-sulfonyliminopiperidine and its reaction with benzyl Grignard to form an important pharmaceutical building block, 4-benzyl-4-aminopiperidne.It can be also used to prepare spiro tosylaziridines via methylene insertion into the derived sulfonylimine1,2-(R)-(+)-2-Methyl-2-propanesulfinamide may be used to prepare N-(1-cyclohexylmethylidene)-2-methylpropane-2-sulfinamide via copper mediated condensation with cyclohexane carboxaldehyde. It may also be used to prepare (20E)-N-[t-butyl-(R)-sulfinyl]-3-(t-butyldimethylsilyloxy)-pregn-5-en-20-imine, an intermediate for the development of androgen receptor antagonists. (S)-(-)-2-Methyl-2-propanesulfinamide may be used to develop benzofuran-based farnesyltransferase inhibitors as anti-cancer agents.

tert-Butanesulfinamide manufacturers

  • tert-Butanesulfinamide
  • US $0.00 / KG
  • 2023-09-05
  • CAS:146374-27-8
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 50000KG/month
  • tert-Butanesulfinamide
  • US $10.70 / Kg/Drum
  • 2023-03-06
  • CAS:146374-27-8
  • Min. Order: 10g
  • Purity: 99%
  • Supply Ability: 10000kg
  • tert-Butanesulfinamide
  • US $0.00-0.00 / kg
  • 2022-09-30
  • CAS:146374-27-8
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 1Ton
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