182815-44-7 Basic information More..
Product Name:Colesevelam
Synonyms:Colesevelam and Colesevelam Hydrochloride;colesevelam hcl API;Colesevelam;2-Propen-1-amine polymer with (chloromethyl)oxirane, N-2-propenyl-1-decanamine and N,N,N-trimethyl-6-(2-propenylamino)-1-hexanaminium chloride hydrochloride;Colesevelam USP/EP/BP;Colesevelam USP;Colesevelam HydrochlorideQ: What is Colesevelam Hydrochloride Q: What is the CAS Number of Colesevelam Hydrochloride Q: What is the storage condition of Colesevelam Hydrochloride Q: What are the applications of Colesevelam Hydrochloride;Colesevelam hydrochloride
CAS:182815-44-7
MF:C31H66Cl2N4O
MW:581.8
EINECS:806-925-3
Mol File:182815-44-7.mol
182815-44-7

Use

Colesevelam hydrochloride was launched as Welchol (formerly known as Cholestagel) in the US for the reduction of elevated levels of serum LDL cholesterol and accordingly, the decrease of the risk of vascular disease in patients with primary hypercholesterolemia. This orally administered cationic hydrogel is a non-absorbable, water-insoluble polymer of an hexanaminium chloride with N-(2-propenyl) decanamine, 2-propen-1-amine hydrochloride and chloromethyloxirane. It acts as a powerful bile acid sequestering agent, this binding and blockage of bile acids having the end result of compelling the removal of LDL cholesterol from the blood stream into the liver.

Colesevelam manufacturers

  • Colesevelam USP/EP/BP
  • US $1.10 / g
  • 2021-08-06
  • CAS:182815-44-7
  • Min. Order: 1g
  • Purity: 99.9%
  • Supply Ability: 100 Tons min
  • Colesevelam
  • US $0.00-0.00 / KG
  • 2020-05-12
  • CAS:182815-44-7
  • Min. Order: 1KG
  • Purity: 99.0%
  • Supply Ability: 500 MT
  • Colesevelam
  • US $1.00 / KG
  • 2020-02-01
  • CAS:182815-44-7
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 200kgs
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