| | 123040-16-4 Basic information More.. |
| Product Name: | Azasetron hydrochloride | | Synonyms: | N-(1-Azabicyclo[2.2.2]octane-3-yl)-6-chloro-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxamide·hydrochloride;6-chloro-3-keto-4-methyl-N-quinuclidin-3-yl-1,4-benzoxazine-8-carboxamide hydrochloride;N-{1-azabicyclo[2.2.2]octan-3-yl}-6-chloro-4-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxaMide;Azastron hydrochloride injection;N-(1-Azabicyclo[2.2.2]oct-3-yl)-6-chloro-4-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxaMide hydrochloride (1:1);N-1-AZABICYCLO[2.2.2]-OCT-3-YL-6-CHLORO-3,4-DIHYDRO-4-METHYL-3-OXO-2H-1,4-BENZOXAZINE-8-CARBOXAMIDE, HYDROCHLORIDE;N-(1-AZABICYCLO[2.2.2]OCT-3-YL)-6-CHLORO-4-METHYL-3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZINE-8-CARBOXAMIDE HCL;N-(1-AZABICYCLO[2.2.2]OCT-3-YL)-6-CHLORO-4-METHYL-3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZINE-8-CARBOXAMIDE HYDROCHLORIDE | | CAS: | 123040-16-4 | | MF: | C17H21Cl2N3O3 | | MW: | 386.27 | | EINECS: | 692-159-3 | | Mol File: | 123040-16-4.mol |  |
Use
Nazasetron (azasetron) hydrochloride is the fourth in the class of highly potent 5-
HT3 receptor antagonists to reach the market for prophylaxis of severe nausea and
vomiting induced by cytotoxic chemotherapy and by total body X-radiation. In a
study with 146 cancer patients suffering from emesis induced by cisplatin,
nazasetron was reported to be markedly effective in 72% of subjects. Nazasetron is
devoid of dopamine D2 receptor blocking activity and therefore is free of the
extrapyrimidal side effects associated with other commonly used antiemetics such
as metoclopramide and domperidone. Nazasetron has been reported to be
potentially useful for the treatment of gastrointestinal motility dysfunction, such as
gastric stasis, vomiting and irritable bowel syndrome.
- Azasetron hydrochloride
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- US $10.00 / kg
- 2023-07-22
- CAS:123040-16-4
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000tons
- Azasetron hydrochloride
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- US $0.00 / Kg/Bag
- 2021-11-04
- CAS:123040-16-4
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 100kg
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123040-16-4
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